Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy

Gene therapy would greatly benefit from a method to regulate therapeutic gene expression temporally. Riboswitches are small RNA elements that have been studied for their potential use in turning transgene expression on or off by ligand binding. We compared several tetracycline and toyocamycin-induci...

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Detalles Bibliográficos
Autores principales: Eriksson, Reetta A. E., Nieminen, Tiina, Galibert, Lionel, Peltola, Sanna K., Tikkanen, Petra, Käyhty, Piia, Leinonen, Hanna M., Oruetxebarria, Igor, Lepola, Saana, Valkama, Anniina J., Lipponen, Eevi M., Lesch, Hanna P., Ylä-Herttuala, Seppo, Airenne, Kari J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792491/
https://www.ncbi.nlm.nih.gov/pubmed/36582287
http://dx.doi.org/10.3389/fmed.2022.1052318

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