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C-type lectin-like receptor (CLEC)-2, the ligand of podoplanin, induces morphological changes in podocytes

Podoplanin (PDPN) is intensely expressed on the podocyte membrane in an evolutionally conserved manner. CLEC-2, the endogenous ligand of PDPN, is highly expressed in platelets and also exists in a soluble form in plasma. Normally, podocytes are sequestered from CLEC-2, but when the glomerular barrie...

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Detalles Bibliográficos
Autores principales:	Tanaka, Keiko, Tanaka, Masafumi, Watanabe, Nobuo, Ito, Masatoshi, Pastan, Ira, Koizumi, Masahiro, Matsusaka, Taiji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792514/ https://www.ncbi.nlm.nih.gov/pubmed/36572741 http://dx.doi.org/10.1038/s41598-022-26456-9

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