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Trends of kidney cancer burden from 1990 to 2019 in European Union 15 + countries and World Health Organization regions
In recent decades, variability in the incidence and mortality of kidney cancer (KC) has been reported. This study aimed to compare trends in incidence, mortality, and disability-adjusted life years (DALY) of KC between the European Union (EU) 15 + countries and 6 World Health Organization (WHO) regi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792551/ https://www.ncbi.nlm.nih.gov/pubmed/36572700 http://dx.doi.org/10.1038/s41598-022-25485-8 |
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author | Jani, Chinmay Abdallah, Nour Mouchati, Christian Jani, Ruchi Sharma, Rajesh Bhatt, Padmanabh Hanbury, Georgina Salciccioli, Justin Singh, Harpreet Shalhoub, Joseph McKay, Rana R. Marshall, Dominic C. |
author_facet | Jani, Chinmay Abdallah, Nour Mouchati, Christian Jani, Ruchi Sharma, Rajesh Bhatt, Padmanabh Hanbury, Georgina Salciccioli, Justin Singh, Harpreet Shalhoub, Joseph McKay, Rana R. Marshall, Dominic C. |
author_sort | Jani, Chinmay |
collection | PubMed |
description | In recent decades, variability in the incidence and mortality of kidney cancer (KC) has been reported. This study aimed to compare trends in incidence, mortality, and disability-adjusted life years (DALY) of KC between the European Union (EU) 15 + countries and 6 World Health Organization (WHO) regions. The data of KC Age-standardized incidence rates (ASIRs), age-standardized mortality rates (ASMRs), and age-standardized DALYs were extracted from the Global Burden of Disease database. Joinpoint regression was employed to examine trends. From 1990 to 2019, the ASIR increased in most countries except for Luxembourg (males), the USA (females) and Austria and Sweden (both sexes). ASIR increased across all 6 WHO regions for both sexes except for females in Americas. The ASMR increased in 10/19 countries for males and 9/19 for females as well across most WHO regions. The mortality-to-incidence ratio (MIR) decreased in all countries and WHO regions. Trends in DALYs were variable across countries and WHO regions. While the incidence and mortality from KC rose in most EU15 + countries and WHO regions from 1990 to 2019, the universal drop in MIR suggests an overall improvement in KC outcomes. This is likely multifactorial, including earlier detection of KC and improved treatments. |
format | Online Article Text |
id | pubmed-9792551 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-97925512022-12-28 Trends of kidney cancer burden from 1990 to 2019 in European Union 15 + countries and World Health Organization regions Jani, Chinmay Abdallah, Nour Mouchati, Christian Jani, Ruchi Sharma, Rajesh Bhatt, Padmanabh Hanbury, Georgina Salciccioli, Justin Singh, Harpreet Shalhoub, Joseph McKay, Rana R. Marshall, Dominic C. Sci Rep Article In recent decades, variability in the incidence and mortality of kidney cancer (KC) has been reported. This study aimed to compare trends in incidence, mortality, and disability-adjusted life years (DALY) of KC between the European Union (EU) 15 + countries and 6 World Health Organization (WHO) regions. The data of KC Age-standardized incidence rates (ASIRs), age-standardized mortality rates (ASMRs), and age-standardized DALYs were extracted from the Global Burden of Disease database. Joinpoint regression was employed to examine trends. From 1990 to 2019, the ASIR increased in most countries except for Luxembourg (males), the USA (females) and Austria and Sweden (both sexes). ASIR increased across all 6 WHO regions for both sexes except for females in Americas. The ASMR increased in 10/19 countries for males and 9/19 for females as well across most WHO regions. The mortality-to-incidence ratio (MIR) decreased in all countries and WHO regions. Trends in DALYs were variable across countries and WHO regions. While the incidence and mortality from KC rose in most EU15 + countries and WHO regions from 1990 to 2019, the universal drop in MIR suggests an overall improvement in KC outcomes. This is likely multifactorial, including earlier detection of KC and improved treatments. Nature Publishing Group UK 2022-12-26 /pmc/articles/PMC9792551/ /pubmed/36572700 http://dx.doi.org/10.1038/s41598-022-25485-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Jani, Chinmay Abdallah, Nour Mouchati, Christian Jani, Ruchi Sharma, Rajesh Bhatt, Padmanabh Hanbury, Georgina Salciccioli, Justin Singh, Harpreet Shalhoub, Joseph McKay, Rana R. Marshall, Dominic C. Trends of kidney cancer burden from 1990 to 2019 in European Union 15 + countries and World Health Organization regions |
title | Trends of kidney cancer burden from 1990 to 2019 in European Union 15 + countries and World Health Organization regions |
title_full | Trends of kidney cancer burden from 1990 to 2019 in European Union 15 + countries and World Health Organization regions |
title_fullStr | Trends of kidney cancer burden from 1990 to 2019 in European Union 15 + countries and World Health Organization regions |
title_full_unstemmed | Trends of kidney cancer burden from 1990 to 2019 in European Union 15 + countries and World Health Organization regions |
title_short | Trends of kidney cancer burden from 1990 to 2019 in European Union 15 + countries and World Health Organization regions |
title_sort | trends of kidney cancer burden from 1990 to 2019 in european union 15 + countries and world health organization regions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792551/ https://www.ncbi.nlm.nih.gov/pubmed/36572700 http://dx.doi.org/10.1038/s41598-022-25485-8 |
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