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Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex

Human cortical organoids, three-dimensional neuronal cultures, are emerging as powerful tools to study brain development and dysfunction. However, whether organoids can functionally connect to a sensory network in vivo has yet to be demonstrated. Here, we combine transparent microelectrode arrays an...

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Detalles Bibliográficos
Autores principales:	Wilson, Madison N., Thunemann, Martin, Liu, Xin, Lu, Yichen, Puppo, Francesca, Adams, Jason W., Kim, Jeong-Hoon, Ramezani, Mehrdad, Pizzo, Donald P., Djurovic, Srdjan, Andreassen, Ole A., Mansour, Abed AlFatah, Gage, Fred H., Muotri, Alysson R., Devor, Anna, Kuzum, Duygu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792589/ https://www.ncbi.nlm.nih.gov/pubmed/36572698 http://dx.doi.org/10.1038/s41467-022-35536-3

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