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Visualizing advances in the future of primate neuroscience research

Future neuroscience and biomedical projects involving non-human primates (NHPs) remain essential in our endeavors to understand the complexities and functioning of the mammalian central nervous system. In so doing, the NHP neuroscience researcher must be allowed to incorporate state-of-the-art techn...

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Autores principales: Janssen, Peter, Isa, Tadashi, Lanciego, Jose, Leech, Kirk, Logothetis, Nikos, Poo, Mu-Ming, Mitchell, Anna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792703/
https://www.ncbi.nlm.nih.gov/pubmed/36582401
http://dx.doi.org/10.1016/j.crneur.2022.100064
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author Janssen, Peter
Isa, Tadashi
Lanciego, Jose
Leech, Kirk
Logothetis, Nikos
Poo, Mu-Ming
Mitchell, Anna S.
author_facet Janssen, Peter
Isa, Tadashi
Lanciego, Jose
Leech, Kirk
Logothetis, Nikos
Poo, Mu-Ming
Mitchell, Anna S.
author_sort Janssen, Peter
collection PubMed
description Future neuroscience and biomedical projects involving non-human primates (NHPs) remain essential in our endeavors to understand the complexities and functioning of the mammalian central nervous system. In so doing, the NHP neuroscience researcher must be allowed to incorporate state-of-the-art technologies, including the use of novel viral vectors, gene therapy and transgenic approaches to answer continuing and emerging research questions that can only be addressed in NHP research models. This perspective piece captures these emerging technologies and some specific research questions they can address. At the same time, we highlight some current caveats to global NHP research and collaborations including the lack of common ethical and regulatory frameworks for NHP research, the limitations involving animal transportation and exports, and the ongoing influence of activist groups opposed to NHP research.
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spelling pubmed-97927032022-12-28 Visualizing advances in the future of primate neuroscience research Janssen, Peter Isa, Tadashi Lanciego, Jose Leech, Kirk Logothetis, Nikos Poo, Mu-Ming Mitchell, Anna S. Curr Res Neurobiol Articles from the special issue: A Global Outlook on Non-Human Primates in Neuroscience Research, edited by Renee Hartig, Anna Mitchell and Chris Petkov Future neuroscience and biomedical projects involving non-human primates (NHPs) remain essential in our endeavors to understand the complexities and functioning of the mammalian central nervous system. In so doing, the NHP neuroscience researcher must be allowed to incorporate state-of-the-art technologies, including the use of novel viral vectors, gene therapy and transgenic approaches to answer continuing and emerging research questions that can only be addressed in NHP research models. This perspective piece captures these emerging technologies and some specific research questions they can address. At the same time, we highlight some current caveats to global NHP research and collaborations including the lack of common ethical and regulatory frameworks for NHP research, the limitations involving animal transportation and exports, and the ongoing influence of activist groups opposed to NHP research. Elsevier 2022-12-13 /pmc/articles/PMC9792703/ /pubmed/36582401 http://dx.doi.org/10.1016/j.crneur.2022.100064 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Articles from the special issue: A Global Outlook on Non-Human Primates in Neuroscience Research, edited by Renee Hartig, Anna Mitchell and Chris Petkov
Janssen, Peter
Isa, Tadashi
Lanciego, Jose
Leech, Kirk
Logothetis, Nikos
Poo, Mu-Ming
Mitchell, Anna S.
Visualizing advances in the future of primate neuroscience research
title Visualizing advances in the future of primate neuroscience research
title_full Visualizing advances in the future of primate neuroscience research
title_fullStr Visualizing advances in the future of primate neuroscience research
title_full_unstemmed Visualizing advances in the future of primate neuroscience research
title_short Visualizing advances in the future of primate neuroscience research
title_sort visualizing advances in the future of primate neuroscience research
topic Articles from the special issue: A Global Outlook on Non-Human Primates in Neuroscience Research, edited by Renee Hartig, Anna Mitchell and Chris Petkov
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792703/
https://www.ncbi.nlm.nih.gov/pubmed/36582401
http://dx.doi.org/10.1016/j.crneur.2022.100064
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