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Dataset of dual RNA-seq mapping in visceral leishmaniasis: Inquiry on parasite transcripts in human blood transcriptome upon Leishmania infantum infection

This dataset is related to the article “Insight Into the Long Noncoding RNA and mRNA Coexpression Profile in the Human Blood Transcriptome Upon Leishmania infantum Infection” by S.R. Maruyama, C.A. Fuzo, A.E.R. Oliveira, L.A. Rogerio, N.T. Takamiya, G. Pessenda, E.V. de Melo, A.M. da Silva, A.R. Jes...

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Detalles Bibliográficos
Autores principales: Gomes, Ellen, Rogerio, Luana Aparecida, Takamiya, Nayore Tamie, Torres, Caroline, da Silva, João Santana, Almeida, Roque Pacheco, Maruyama, Sandra Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792721/
https://www.ncbi.nlm.nih.gov/pubmed/36582994
http://dx.doi.org/10.1016/j.dib.2022.108811
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author Gomes, Ellen
Rogerio, Luana Aparecida
Takamiya, Nayore Tamie
Torres, Caroline
da Silva, João Santana
Almeida, Roque Pacheco
Maruyama, Sandra Regina
author_facet Gomes, Ellen
Rogerio, Luana Aparecida
Takamiya, Nayore Tamie
Torres, Caroline
da Silva, João Santana
Almeida, Roque Pacheco
Maruyama, Sandra Regina
author_sort Gomes, Ellen
collection PubMed
description This dataset is related to the article “Insight Into the Long Noncoding RNA and mRNA Coexpression Profile in the Human Blood Transcriptome Upon Leishmania infantum Infection” by S.R. Maruyama, C.A. Fuzo, A.E.R. Oliveira, L.A. Rogerio, N.T. Takamiya, G. Pessenda, E.V. de Melo, A.M. da Silva, A.R. Jesus, V. Carregaro, H.I. Nakaya, R.P. Almeida and J.S. da Silva. Frontiers in Immunology, 2022. Through the reuse of raw sequencing data, we generated original dataset by performing a dual RNA-seq mapping procedure to survey the parasite transcripts found in RNA-seq samples from blood of visceral leishmaniasis patients. Diseased patients with active infection displayed the highest number of reads mapped to L. infantum genome. Even after six months later of the treatment, when the patients were considered cured, parasite reads were still detected. Parasite reads were also detected in asymptomatic individuals. The original dual RNA-seq alignment read count data provided here can be further explored to evaluate either host or parasite transcripts.
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spelling pubmed-97927212022-12-28 Dataset of dual RNA-seq mapping in visceral leishmaniasis: Inquiry on parasite transcripts in human blood transcriptome upon Leishmania infantum infection Gomes, Ellen Rogerio, Luana Aparecida Takamiya, Nayore Tamie Torres, Caroline da Silva, João Santana Almeida, Roque Pacheco Maruyama, Sandra Regina Data Brief Data Article This dataset is related to the article “Insight Into the Long Noncoding RNA and mRNA Coexpression Profile in the Human Blood Transcriptome Upon Leishmania infantum Infection” by S.R. Maruyama, C.A. Fuzo, A.E.R. Oliveira, L.A. Rogerio, N.T. Takamiya, G. Pessenda, E.V. de Melo, A.M. da Silva, A.R. Jesus, V. Carregaro, H.I. Nakaya, R.P. Almeida and J.S. da Silva. Frontiers in Immunology, 2022. Through the reuse of raw sequencing data, we generated original dataset by performing a dual RNA-seq mapping procedure to survey the parasite transcripts found in RNA-seq samples from blood of visceral leishmaniasis patients. Diseased patients with active infection displayed the highest number of reads mapped to L. infantum genome. Even after six months later of the treatment, when the patients were considered cured, parasite reads were still detected. Parasite reads were also detected in asymptomatic individuals. The original dual RNA-seq alignment read count data provided here can be further explored to evaluate either host or parasite transcripts. Elsevier 2022-12-08 /pmc/articles/PMC9792721/ /pubmed/36582994 http://dx.doi.org/10.1016/j.dib.2022.108811 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Data Article
Gomes, Ellen
Rogerio, Luana Aparecida
Takamiya, Nayore Tamie
Torres, Caroline
da Silva, João Santana
Almeida, Roque Pacheco
Maruyama, Sandra Regina
Dataset of dual RNA-seq mapping in visceral leishmaniasis: Inquiry on parasite transcripts in human blood transcriptome upon Leishmania infantum infection
title Dataset of dual RNA-seq mapping in visceral leishmaniasis: Inquiry on parasite transcripts in human blood transcriptome upon Leishmania infantum infection
title_full Dataset of dual RNA-seq mapping in visceral leishmaniasis: Inquiry on parasite transcripts in human blood transcriptome upon Leishmania infantum infection
title_fullStr Dataset of dual RNA-seq mapping in visceral leishmaniasis: Inquiry on parasite transcripts in human blood transcriptome upon Leishmania infantum infection
title_full_unstemmed Dataset of dual RNA-seq mapping in visceral leishmaniasis: Inquiry on parasite transcripts in human blood transcriptome upon Leishmania infantum infection
title_short Dataset of dual RNA-seq mapping in visceral leishmaniasis: Inquiry on parasite transcripts in human blood transcriptome upon Leishmania infantum infection
title_sort dataset of dual rna-seq mapping in visceral leishmaniasis: inquiry on parasite transcripts in human blood transcriptome upon leishmania infantum infection
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792721/
https://www.ncbi.nlm.nih.gov/pubmed/36582994
http://dx.doi.org/10.1016/j.dib.2022.108811
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