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Long-Term Exposure to Morphine Induces Cross-Tolerance to Acute Antinociceptive Effect of Remifentanil on Somatic and Visceral Stimuli in Rats

PURPOSE: Remifentanil is one of the most commonly used opioids intraoperatively. Previous reports indicate that long-term use of opioids may lead to cross-tolerance to remifentanil, which poses a challenge in the control of acute pain intraoperatively. However, there is limited information regarding...

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Detalles Bibliográficos
Autores principales:	Mori, Hideaki, Hashimoto, Tatsuya, Nikai, Tetsuro, Furuya, Motohide, Hattori, Mai, Katsube, Yukiko, Saito, Yoji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792809/ https://www.ncbi.nlm.nih.gov/pubmed/36582657 http://dx.doi.org/10.2147/JPR.S389929

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