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Intact provirus and integration sites analysis in acute HIV-1 infection and changes after one year of early antiviral therapy
BACKGROUND AND OBJECTIVES: HIV-1 provirus integration in host genomes provides a lifelong reservoir of virally infected cells. Although not able to generate viral progeny, the expression of defective proviruses has been associated with activation. Provirus integration may influence host gene transcr...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792883/ https://www.ncbi.nlm.nih.gov/pubmed/36582472 http://dx.doi.org/10.1016/j.jve.2022.100306 |