Intact provirus and integration sites analysis in acute HIV-1 infection and changes after one year of early antiviral therapy

BACKGROUND AND OBJECTIVES: HIV-1 provirus integration in host genomes provides a lifelong reservoir of virally infected cells. Although not able to generate viral progeny, the expression of defective proviruses has been associated with activation. Provirus integration may influence host gene transcr...

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Detalles Bibliográficos
Autores principales: Rozera, Gabriella, Sberna, Giuseppe, Berno, Giulia, Gruber, Cesare Ernesto Maria, Giombini, Emanuela, Spezia, Pietro Giorgio, Orchi, Nicoletta, Puro, Vincenzo, Mondi, Annalisa, Girardi, Enrico, Vaia, Francesco, Antinori, Andrea, Maggi, Fabrizio, Abbate, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792883/
https://www.ncbi.nlm.nih.gov/pubmed/36582472
http://dx.doi.org/10.1016/j.jve.2022.100306

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