Wnt antagonism without TGFβ induces rapid MSC chondrogenesis via increasing AJ interactions and restricting lineage commitment

Human mesenchymal stem cells (MSCs) remain one of the best cell sources for cartilage, a tissue without regenerative capacity. However, MSC chondrogenesis is commonly induced through TGFβ, a pleomorphic growth factor without specificity for this lineage. Using tissue- and induced pluripotent stem ce...

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Detalles Bibliográficos
Autores principales: Hsieh, Chen-Chan, Yen, B. Linju, Chang, Chia-Chi, Hsu, Pei-Ju, Lee, Yu-Wei, Yen, Men-Luh, Yet, Shaw-Fang, Chen, Linyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792887/
https://www.ncbi.nlm.nih.gov/pubmed/36582823
http://dx.doi.org/10.1016/j.isci.2022.105713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792887/
https://www.ncbi.nlm.nih.gov/pubmed/36582823
http://dx.doi.org/10.1016/j.isci.2022.105713

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