Erythroid SLC7A5/SLC3A2 amino acid carrier controls red blood cell size and maturation

Inhibition of the heterodimeric amino acid carrier SLC7A5/SLC3A2 (LAT1/CD98) has been widely studied in tumor biology but its role in physiological conditions remains largely unknown. Here we show that the SLC7A5/SLC3A2 heterodimer is constitutively present at different stages of erythroid different...

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Detalles Bibliográficos
Autores principales: Bouthelier, Antonio, Fernández-Arroyo, Lucía, Mesa-Ciller, Claudia, Cibrian, Danay, Martín-Cófreces, Noa Beatriz, Castillo-González, Raquel, Calero, Macarena, Herráez-Aguilar, Diego, Guajardo-Grence, Andrea, Pacheco, Ana María, Marcos-Jiménez, Ana, Quiroga, Borja, Morado, Marta, Monroy, Francisco, Muñoz-Calleja, Cecilia, Sánchez-Madrid, Francisco, Urrutia, Andrés A., Aragonés, Julián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792907/
https://www.ncbi.nlm.nih.gov/pubmed/36582828
http://dx.doi.org/10.1016/j.isci.2022.105739

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