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Rickettsial pathogen inhibits tick cell death through tryptophan metabolite mediated activation of p38 MAP kinase

Anaplasma phagocytophilum modulates various cell signaling pathways in mammalian cells for its survival. In this study, we report that A. phagocytophilum modulates tick tryptophan pathway to activate arthropod p38 MAP kinase for the survival of both this bacterium and its vector host. Increased leve...

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Detalles Bibliográficos
Autores principales: Namjoshi, Prachi, Dahmani, Mustapha, Sultana, Hameeda, Neelakanta, Girish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792911/
https://www.ncbi.nlm.nih.gov/pubmed/36582833
http://dx.doi.org/10.1016/j.isci.2022.105730