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Similar programmed death ligand 1 (PD-L1) expression profile in patients with mild COPD and lung cancer
Programmed Death Ligand 1 (PD-L1) is crucial in regulating the immunological tolerance in non-small cell lung cancer (NSCLC). Alveolar macrophage (AM)-derived PD-L1 binds to its receptor, PD-1, on surveilling lymphocytes, leading to lymphocyte exhaustion. Increased PD-L1 expression is associated wit...
Autores principales: | Polverino, F., Mirra, D., Yang, C. X., Esposito, R., Spaziano, G., Rojas-Quintero, J., Sgambato, M., Piegari, E., Cozzolino, A., Cione, E., Gallelli, L., Capuozzo, A., Santoriello, C., Berrino, L., de- Torres, J. P., Hackett, T. L., Polverino, M., D’Agostino, B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792927/ https://www.ncbi.nlm.nih.gov/pubmed/36575294 http://dx.doi.org/10.1038/s41598-022-26650-9 |
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