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Chemically defined generation of human definitive hematopoietic stem and progenitor cells

Here, we present a protocol to efficiently direct human pluripotent stem cells (hPSCs) into hematopoietic stem and progenitor cells (HSPCs) under a chemically defined, albumin-free system. We describe the induction of aorta-gonad-mesonephros-like hematopoiesis from hPSCs into SOX17+ hemogenic endoth...

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Detalles Bibliográficos
Autores principales:	Jung, Juhyung, Chang, Yun, Jin, Gyuhyung, Deng, Qing, Lian, Xiaojun Lance, Bao, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792952/ https://www.ncbi.nlm.nih.gov/pubmed/36527716 http://dx.doi.org/10.1016/j.xpro.2022.101953

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