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Synthesis and characterization of semisynthetic analogs of the antifungal occidiofungin

Occidiofungin is a broad-spectrum antifungal compound produced by Burkholderia contaminans MS14. It is a cyclic glycol-lipopeptide with a novel beta-amino acid (NAA2) containing a hydroxylated C18 fatty acid chain with a xylose sugar. This study reports a strategy to produce semisynthetic analogs of...

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Detalles Bibliográficos
Autores principales: Geng, Mengxin, Hansanant, Nopakorn, Lu, Shi-En, Lockless, Steve W., Shin, Ronald, Orugunty, Ravi, Smith, Leif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792986/
https://www.ncbi.nlm.nih.gov/pubmed/36583054
http://dx.doi.org/10.3389/fmicb.2022.1056453