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Psychotic symptoms in a patient with Systemic Lupus Erythematosus: A diagnostic dilemma between lupus psychosis and steroid induced psychosis
INTRODUCTION: Systemic Lupus Erythematosus (SLE) is a chronic auto-immune disorder with the involvement of multiple organ systems. It is more common in females. CASE PRESENTATION: Here, we present a case of 12-year-old female, known case of SLE with lupus nephritis, presenting with neuropsychiatric...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793111/ https://www.ncbi.nlm.nih.gov/pubmed/36582883 http://dx.doi.org/10.1016/j.amsu.2022.104843 |
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author | Pathak, Bishnu Deep Regmi, Binit Upadhaya Dhakal, Bishal Joshi, Sushil Simkhada, Nabin Sapkota, Suhail Joshi, Sushant Thapa, Sujan Rana |
author_facet | Pathak, Bishnu Deep Regmi, Binit Upadhaya Dhakal, Bishal Joshi, Sushil Simkhada, Nabin Sapkota, Suhail Joshi, Sushant Thapa, Sujan Rana |
author_sort | Pathak, Bishnu Deep |
collection | PubMed |
description | INTRODUCTION: Systemic Lupus Erythematosus (SLE) is a chronic auto-immune disorder with the involvement of multiple organ systems. It is more common in females. CASE PRESENTATION: Here, we present a case of 12-year-old female, known case of SLE with lupus nephritis, presenting with neuropsychiatric symptoms. She was under steroids as well for a few weeks due to flare-up of symptoms prior to that. Due to this, there was a diagnostic dilemma between lupus psychosis and steroid induced psychosis. CLINICAL DISCUSSION: Approximately one third to half of the patients may have neurological involvement in Systemic Lupus Erythematosus. However, neuropsychiatric symptoms in them could be due to corticosteroids, which are frequently used in treatment. There are no definitive and easily available laboratory markers to distinguish these two aetiologies. CONCLUSIONS: Systemic Lupus Erythematosus patients, who are on steroids, with neuropsychiatric features should be assessed adequately. As there are no specific guideline and biomarkers to distinguish between these two, meticulous evaluation is necessary for appropriate management. |
format | Online Article Text |
id | pubmed-9793111 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-97931112022-12-28 Psychotic symptoms in a patient with Systemic Lupus Erythematosus: A diagnostic dilemma between lupus psychosis and steroid induced psychosis Pathak, Bishnu Deep Regmi, Binit Upadhaya Dhakal, Bishal Joshi, Sushil Simkhada, Nabin Sapkota, Suhail Joshi, Sushant Thapa, Sujan Rana Ann Med Surg (Lond) Case Report INTRODUCTION: Systemic Lupus Erythematosus (SLE) is a chronic auto-immune disorder with the involvement of multiple organ systems. It is more common in females. CASE PRESENTATION: Here, we present a case of 12-year-old female, known case of SLE with lupus nephritis, presenting with neuropsychiatric symptoms. She was under steroids as well for a few weeks due to flare-up of symptoms prior to that. Due to this, there was a diagnostic dilemma between lupus psychosis and steroid induced psychosis. CLINICAL DISCUSSION: Approximately one third to half of the patients may have neurological involvement in Systemic Lupus Erythematosus. However, neuropsychiatric symptoms in them could be due to corticosteroids, which are frequently used in treatment. There are no definitive and easily available laboratory markers to distinguish these two aetiologies. CONCLUSIONS: Systemic Lupus Erythematosus patients, who are on steroids, with neuropsychiatric features should be assessed adequately. As there are no specific guideline and biomarkers to distinguish between these two, meticulous evaluation is necessary for appropriate management. Elsevier 2022-11-07 /pmc/articles/PMC9793111/ /pubmed/36582883 http://dx.doi.org/10.1016/j.amsu.2022.104843 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Pathak, Bishnu Deep Regmi, Binit Upadhaya Dhakal, Bishal Joshi, Sushil Simkhada, Nabin Sapkota, Suhail Joshi, Sushant Thapa, Sujan Rana Psychotic symptoms in a patient with Systemic Lupus Erythematosus: A diagnostic dilemma between lupus psychosis and steroid induced psychosis |
title | Psychotic symptoms in a patient with Systemic Lupus Erythematosus: A diagnostic dilemma between lupus psychosis and steroid induced psychosis |
title_full | Psychotic symptoms in a patient with Systemic Lupus Erythematosus: A diagnostic dilemma between lupus psychosis and steroid induced psychosis |
title_fullStr | Psychotic symptoms in a patient with Systemic Lupus Erythematosus: A diagnostic dilemma between lupus psychosis and steroid induced psychosis |
title_full_unstemmed | Psychotic symptoms in a patient with Systemic Lupus Erythematosus: A diagnostic dilemma between lupus psychosis and steroid induced psychosis |
title_short | Psychotic symptoms in a patient with Systemic Lupus Erythematosus: A diagnostic dilemma between lupus psychosis and steroid induced psychosis |
title_sort | psychotic symptoms in a patient with systemic lupus erythematosus: a diagnostic dilemma between lupus psychosis and steroid induced psychosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793111/ https://www.ncbi.nlm.nih.gov/pubmed/36582883 http://dx.doi.org/10.1016/j.amsu.2022.104843 |
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