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Early surgery and definitive cure in small sporadic vestibular schwannoma

OBJECTIVE: To report surgical outcomes of a cohort of small sporadic vestibular schwannoma and discuss the role of early surgery. METHODS: Retrospective descriptive analysis of 234 consecutive patients with small vestibular schwannoma operated on with translabyrinthine or hearing preservation surgic...

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Autores principales: Zanoletti, Elisabetta, Concheri, Stefano, Tealdo, Giulia, Cazzador, Diego, Denaro, Luca, d’Avella, Domenico, Mazzoni, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore Srl 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793146/
https://www.ncbi.nlm.nih.gov/pubmed/36541386
http://dx.doi.org/10.14639/0392-100X-N2322
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author Zanoletti, Elisabetta
Concheri, Stefano
Tealdo, Giulia
Cazzador, Diego
Denaro, Luca
d’Avella, Domenico
Mazzoni, Antonio
author_facet Zanoletti, Elisabetta
Concheri, Stefano
Tealdo, Giulia
Cazzador, Diego
Denaro, Luca
d’Avella, Domenico
Mazzoni, Antonio
author_sort Zanoletti, Elisabetta
collection PubMed
description OBJECTIVE: To report surgical outcomes of a cohort of small sporadic vestibular schwannoma and discuss the role of early surgery. METHODS: Retrospective descriptive analysis of 234 consecutive patients with small vestibular schwannoma operated on with translabyrinthine or hearing preservation surgical approaches. Outcome measures were control of disease, postoperative facial nerve function, complications and hearing outcome. RESULTS: A translabyrinthine approach was performed in 59% of cases, hearing preservation surgery in 40% and transmeatal approach in 1%, respectively. Complete resection was achieved in 100% of cases. Overall, postoperative major and minor complications were 8.5% in the series, with complete recovery and no sequalae. Facial nerve function at one year postoperatively was House-Brackmann scale (HB) 1-2 in 95% of cases. The rate of hearing preservation was 70% A-B-C classes of Tokyo classification and 77% AB classes of AAOHNS classification. CONCLUSIONS: Early surgery in small vestibular schwannoma is a valid option, due to good functional outcomes, low morbidity and definitive cure. Early surgery is associated with better outcomes when considered in relation to non-surgical treatments reported in the literature.
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spelling pubmed-97931462023-01-06 Early surgery and definitive cure in small sporadic vestibular schwannoma Zanoletti, Elisabetta Concheri, Stefano Tealdo, Giulia Cazzador, Diego Denaro, Luca d’Avella, Domenico Mazzoni, Antonio Acta Otorhinolaryngol Ital Skull Base Surgery OBJECTIVE: To report surgical outcomes of a cohort of small sporadic vestibular schwannoma and discuss the role of early surgery. METHODS: Retrospective descriptive analysis of 234 consecutive patients with small vestibular schwannoma operated on with translabyrinthine or hearing preservation surgical approaches. Outcome measures were control of disease, postoperative facial nerve function, complications and hearing outcome. RESULTS: A translabyrinthine approach was performed in 59% of cases, hearing preservation surgery in 40% and transmeatal approach in 1%, respectively. Complete resection was achieved in 100% of cases. Overall, postoperative major and minor complications were 8.5% in the series, with complete recovery and no sequalae. Facial nerve function at one year postoperatively was House-Brackmann scale (HB) 1-2 in 95% of cases. The rate of hearing preservation was 70% A-B-C classes of Tokyo classification and 77% AB classes of AAOHNS classification. CONCLUSIONS: Early surgery in small vestibular schwannoma is a valid option, due to good functional outcomes, low morbidity and definitive cure. Early surgery is associated with better outcomes when considered in relation to non-surgical treatments reported in the literature. Pacini Editore Srl 2022-10-31 2022-10 /pmc/articles/PMC9793146/ /pubmed/36541386 http://dx.doi.org/10.14639/0392-100X-N2322 Text en Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Rome, Italy https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license. The article can be used by giving appropriate credit and mentioning the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en
spellingShingle Skull Base Surgery
Zanoletti, Elisabetta
Concheri, Stefano
Tealdo, Giulia
Cazzador, Diego
Denaro, Luca
d’Avella, Domenico
Mazzoni, Antonio
Early surgery and definitive cure in small sporadic vestibular schwannoma
title Early surgery and definitive cure in small sporadic vestibular schwannoma
title_full Early surgery and definitive cure in small sporadic vestibular schwannoma
title_fullStr Early surgery and definitive cure in small sporadic vestibular schwannoma
title_full_unstemmed Early surgery and definitive cure in small sporadic vestibular schwannoma
title_short Early surgery and definitive cure in small sporadic vestibular schwannoma
title_sort early surgery and definitive cure in small sporadic vestibular schwannoma
topic Skull Base Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793146/
https://www.ncbi.nlm.nih.gov/pubmed/36541386
http://dx.doi.org/10.14639/0392-100X-N2322
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