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Targeted lung denervation modulates the mucosal epithelial transcriptome in COPD
This study shows that TLD reduces airway epithelial expression of genes related to acetylcholine processing and airway inflammation, which may help to elucidate the mechanism for its effect of reducing severe exacerbations in COPD https://bit.ly/3dWcqZk
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Respiratory Society
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793243/ https://www.ncbi.nlm.nih.gov/pubmed/36578630 http://dx.doi.org/10.1183/23120541.00146-2022 |
| _version_ | 1784859813598986240 |
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| author | Srikanthan, Karthi Kistemaker, Loes Slebos, Dirk-Jan Gesierich, Wolfgang Darwiche, Kaid Bonta, Peter Deslee, Gaetan Shah, Pallav Gosens, Reinoud |
| author_facet | Srikanthan, Karthi Kistemaker, Loes Slebos, Dirk-Jan Gesierich, Wolfgang Darwiche, Kaid Bonta, Peter Deslee, Gaetan Shah, Pallav Gosens, Reinoud |
| author_sort | Srikanthan, Karthi |
| collection | PubMed |
| description | This study shows that TLD reduces airway epithelial expression of genes related to acetylcholine processing and airway inflammation, which may help to elucidate the mechanism for its effect of reducing severe exacerbations in COPD https://bit.ly/3dWcqZk |
| format | Online Article Text |
| id | pubmed-9793243 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | European Respiratory Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-97932432022-12-27 Targeted lung denervation modulates the mucosal epithelial transcriptome in COPD Srikanthan, Karthi Kistemaker, Loes Slebos, Dirk-Jan Gesierich, Wolfgang Darwiche, Kaid Bonta, Peter Deslee, Gaetan Shah, Pallav Gosens, Reinoud ERJ Open Res Research Letters This study shows that TLD reduces airway epithelial expression of genes related to acetylcholine processing and airway inflammation, which may help to elucidate the mechanism for its effect of reducing severe exacerbations in COPD https://bit.ly/3dWcqZk European Respiratory Society 2022-12-27 /pmc/articles/PMC9793243/ /pubmed/36578630 http://dx.doi.org/10.1183/23120541.00146-2022 Text en Copyright ©The authors 2022 https://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org) |
| spellingShingle | Research Letters Srikanthan, Karthi Kistemaker, Loes Slebos, Dirk-Jan Gesierich, Wolfgang Darwiche, Kaid Bonta, Peter Deslee, Gaetan Shah, Pallav Gosens, Reinoud Targeted lung denervation modulates the mucosal epithelial transcriptome in COPD |
| title | Targeted lung denervation modulates the mucosal epithelial transcriptome in COPD |
| title_full | Targeted lung denervation modulates the mucosal epithelial transcriptome in COPD |
| title_fullStr | Targeted lung denervation modulates the mucosal epithelial transcriptome in COPD |
| title_full_unstemmed | Targeted lung denervation modulates the mucosal epithelial transcriptome in COPD |
| title_short | Targeted lung denervation modulates the mucosal epithelial transcriptome in COPD |
| title_sort | targeted lung denervation modulates the mucosal epithelial transcriptome in copd |
| topic | Research Letters |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793243/ https://www.ncbi.nlm.nih.gov/pubmed/36578630 http://dx.doi.org/10.1183/23120541.00146-2022 |
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