Impaired synaptic plasticity in an animal model of autism exhibiting early hippocampal GABAergic-BDNF/TrkB signaling alterations

In Neurodevelopmental Disorders, alterations of synaptic plasticity may trigger structural changes in neuronal circuits involved in cognitive functions. This hypothesis was tested in mice carrying the human R451C mutation of Nlgn3 gene (NLG3(R451C) KI), found in some families with autistic children....

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Detalles Bibliográficos
Autores principales: Sgritta, Martina, Vignoli, Beatrice, Pimpinella, Domenico, Griguoli, Marilena, Santi, Spartaco, Bialowas, Andrzej, Wiera, Grzegorz, Zacchi, Paola, Malerba, Francesca, Marchetti, Cristina, Canossa, Marco, Cherubini, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793278/
https://www.ncbi.nlm.nih.gov/pubmed/36582822
http://dx.doi.org/10.1016/j.isci.2022.105728

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