Obtaining the necessary molybdenum cofactor for sulfite oxidase activity in the nematode Caenorhabditis elegans surprisingly involves a dietary source

Molybdenum cofactor (Moco) is a prosthetic group necessary for the activity of four unique enzymes, including the essential sulfite oxidase (SUOX-1). Moco is required for life; humans with inactivating mutations in the genes encoding Moco-biosynthetic enzymes display Moco deficiency, a rare and leth...

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Detalles Bibliográficos
Autores principales: Oliphant, Kevin D., Fettig, Robin R., Snoozy, Jennifer, Mendel, Ralf R., Warnhoff, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793310/
https://www.ncbi.nlm.nih.gov/pubmed/36423681
http://dx.doi.org/10.1016/j.jbc.2022.102736

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