The first-line antituberculosis drugs, and their fixed-dose combination induced abnormal sperm morphology and histological lesions in the testicular cells of male mice

Rifampicin (RIF), Isoniazid (INH), Ethambutol (EMB), Pyrazinamide (PZA), and/or their fixed-dose combination (FDC) are extensively prescribed in the cure of Tuberculosis (TB) globally. In spite of the beneficial effect, these drugs are capable of inducing cellular toxicity. Existing information on t...

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Detalles Bibliográficos
Autores principales: Bakare, Adekunle A., Moses, Victoria Y., Beckely, Charles T., Oluyemi, Toluwani I., Ogunfeitimi, Gift O., Adelaja, Aduragbemi A., Ayorinde, Glory T., Gbadebo, Adeyinka M., Fagbenro, Olukunle S., Ogunsuyi, Olusegun I., Ogunsuyi, Opeoluwa M., Ige, Olusoji Mayowa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793334/
https://www.ncbi.nlm.nih.gov/pubmed/36582470
http://dx.doi.org/10.3389/fcell.2022.1023413

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