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Food effect risk assessment in preformulation stage using material sparing μFLUX methodology
The intake of food and meal type can strongly impact the bioavailability of orally administered drugs and can consequently impact drug efficacy and safety. During the early stages of drug development, only a small amount of drug substance is available, and the solubility difference between fasted st...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Association of Physical Chemists
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793460/ https://www.ncbi.nlm.nih.gov/pubmed/36578564 http://dx.doi.org/10.5599/admet.1476 |