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Resolving morphogenesis into quantifiable cell behaviours

Morphogenesis is extremely diverse, but its systematic quantification to determine the physical mechanisms that produce different phenotypes is possible by quantifying the underlying cell behaviours. These are limited and definable: they consist of cell proliferation, orientation of cell division, c...

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Detalles Bibliográficos
Autor principal: Green, Jeremy B. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793467/
https://www.ncbi.nlm.nih.gov/pubmed/36373721
http://dx.doi.org/10.1242/dev.199794
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author Green, Jeremy B. A.
author_facet Green, Jeremy B. A.
author_sort Green, Jeremy B. A.
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description Morphogenesis is extremely diverse, but its systematic quantification to determine the physical mechanisms that produce different phenotypes is possible by quantifying the underlying cell behaviours. These are limited and definable: they consist of cell proliferation, orientation of cell division, cell rearrangement, directional matrix production, cell addition/subtraction and cell size/shape change. Although minor variations in these categories are possible, in sum they capture all possible morphogenetic behaviours. This article summarises these processes, discusses their measurement, and highlights some salient examples.
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spelling pubmed-97934672023-01-17 Resolving morphogenesis into quantifiable cell behaviours Green, Jeremy B. A. Development Development at A Glance Morphogenesis is extremely diverse, but its systematic quantification to determine the physical mechanisms that produce different phenotypes is possible by quantifying the underlying cell behaviours. These are limited and definable: they consist of cell proliferation, orientation of cell division, cell rearrangement, directional matrix production, cell addition/subtraction and cell size/shape change. Although minor variations in these categories are possible, in sum they capture all possible morphogenetic behaviours. This article summarises these processes, discusses their measurement, and highlights some salient examples. The Company of Biologists Ltd 2022-11-14 /pmc/articles/PMC9793467/ /pubmed/36373721 http://dx.doi.org/10.1242/dev.199794 Text en © 2022. Published by The Company of Biologists Ltd https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Development at A Glance
Green, Jeremy B. A.
Resolving morphogenesis into quantifiable cell behaviours
title Resolving morphogenesis into quantifiable cell behaviours
title_full Resolving morphogenesis into quantifiable cell behaviours
title_fullStr Resolving morphogenesis into quantifiable cell behaviours
title_full_unstemmed Resolving morphogenesis into quantifiable cell behaviours
title_short Resolving morphogenesis into quantifiable cell behaviours
title_sort resolving morphogenesis into quantifiable cell behaviours
topic Development at A Glance
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793467/
https://www.ncbi.nlm.nih.gov/pubmed/36373721
http://dx.doi.org/10.1242/dev.199794
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