Lung shunt fraction quantification methods in radioembolization: What you need to know

In some patients undergoing radioembolization, lung toxicity is a limiting factor when calculating their dose. At the same time, it is known that the lung shunt fraction (LSF) is overestimated by the mapping exam. Furthermore, there are multiple methods to measure LSF. Planar measurement is both the...

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Detalles Bibliográficos
Autores principales: Torkian, Pooya, Ragulojan, Ranjan, J. Woodhead, Gregory, D'Souza, Donna, Flanagan, Siobhan, Golzarian, Jafar, Young, Shamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793490/
https://www.ncbi.nlm.nih.gov/pubmed/35848755
http://dx.doi.org/10.1259/bjr.20220470
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author Torkian, Pooya
Ragulojan, Ranjan
J. Woodhead, Gregory
D'Souza, Donna
Flanagan, Siobhan
Golzarian, Jafar
Young, Shamar
author_facet Torkian, Pooya
Ragulojan, Ranjan
J. Woodhead, Gregory
D'Souza, Donna
Flanagan, Siobhan
Golzarian, Jafar
Young, Shamar
author_sort Torkian, Pooya
collection PubMed
description In some patients undergoing radioembolization, lung toxicity is a limiting factor when calculating their dose. At the same time, it is known that the lung shunt fraction (LSF) is overestimated by the mapping exam. Furthermore, there are multiple methods to measure LSF. Planar measurement is both the most commonly utilized and easiest to perform, however new dosimetry software provides the ability to use more advanced 3D techniques. This paper reviews the different LSF calculation methods and elucidates the available data comparing the techniques, clinical relevance, and dose calculation.
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spelling pubmed-97934902023-01-06 Lung shunt fraction quantification methods in radioembolization: What you need to know Torkian, Pooya Ragulojan, Ranjan J. Woodhead, Gregory D'Souza, Donna Flanagan, Siobhan Golzarian, Jafar Young, Shamar Br J Radiol Review Article In some patients undergoing radioembolization, lung toxicity is a limiting factor when calculating their dose. At the same time, it is known that the lung shunt fraction (LSF) is overestimated by the mapping exam. Furthermore, there are multiple methods to measure LSF. Planar measurement is both the most commonly utilized and easiest to perform, however new dosimetry software provides the ability to use more advanced 3D techniques. This paper reviews the different LSF calculation methods and elucidates the available data comparing the techniques, clinical relevance, and dose calculation. The British Institute of Radiology. 2022-11-01 2022-07-25 /pmc/articles/PMC9793490/ /pubmed/35848755 http://dx.doi.org/10.1259/bjr.20220470 Text en © 2022 The Authors. Published by the British Institute of Radiology https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Review Article
Torkian, Pooya
Ragulojan, Ranjan
J. Woodhead, Gregory
D'Souza, Donna
Flanagan, Siobhan
Golzarian, Jafar
Young, Shamar
Lung shunt fraction quantification methods in radioembolization: What you need to know
title Lung shunt fraction quantification methods in radioembolization: What you need to know
title_full Lung shunt fraction quantification methods in radioembolization: What you need to know
title_fullStr Lung shunt fraction quantification methods in radioembolization: What you need to know
title_full_unstemmed Lung shunt fraction quantification methods in radioembolization: What you need to know
title_short Lung shunt fraction quantification methods in radioembolization: What you need to know
title_sort lung shunt fraction quantification methods in radioembolization: what you need to know
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793490/
https://www.ncbi.nlm.nih.gov/pubmed/35848755
http://dx.doi.org/10.1259/bjr.20220470
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