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Combination of Quercetin or/and siRNA-loaded DDAB-mPEG-PCL hybrid nanoparticles reverse resistance to Regorafenib in colon cancer cells
BACKGROUND: Colorectal cancer (CRC) is the second leading cause of cancer death. Although Regorafenib showed survival benefits in patients with CRC, reports imply the recurrence of malignant phenotype resulting from chemotherapy. Evidence demonstrated that a5β1 integrin plays an important role in th...
Autores principales: | Shahidi, Shabnam, Rostamizadeh, Kobra, Fathi, Mojtaba, Nedaei, Keivan, Ramazani, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793538/ https://www.ncbi.nlm.nih.gov/pubmed/36575448 http://dx.doi.org/10.1186/s12906-022-03787-8 |
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