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Combination of Quercetin or/and siRNA-loaded DDAB-mPEG-PCL hybrid nanoparticles reverse resistance to Regorafenib in colon cancer cells

BACKGROUND: Colorectal cancer (CRC) is the second leading cause of cancer death. Although Regorafenib showed survival benefits in patients with CRC, reports imply the recurrence of malignant phenotype resulting from chemotherapy. Evidence demonstrated that a5β1 integrin plays an important role in th...

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Detalles Bibliográficos
Autores principales: Shahidi, Shabnam, Rostamizadeh, Kobra, Fathi, Mojtaba, Nedaei, Keivan, Ramazani, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793538/
https://www.ncbi.nlm.nih.gov/pubmed/36575448
http://dx.doi.org/10.1186/s12906-022-03787-8

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