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Describing the growth and nutritional status of sickle cell disease children and adolescents with reference to WHO growth standards in Cameroon
BACKGROUND: Sickle cell disease (SCD) is a chronic disease with many complications among which is growth retardation. Here, we described the growth and nutritional status patterns of children with SCD and adolescents living in Douala, Cameroon. METHODS: This cross-sectional study took place at the s...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793582/ https://www.ncbi.nlm.nih.gov/pubmed/36575492 http://dx.doi.org/10.1186/s40795-022-00650-4 |
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author | Charlotte, Eposse Ekoube Ritha Carole, Mbono Betoko Calixthe, Ida Penda Jeanne Georgette, Mony Elimbi Patricia, Epee Iyawa, Hassanatou Edgar, Mandeng Ma Linwa Michael Ngenge, Budzi Gaelle, Ntsoli Kofane Claudia, Ekame Bulu Bianca Dicka, Sajida Misse Paul, Koki Ndombo Daniele-Christiane, Kedy Mangamba Koum |
author_facet | Charlotte, Eposse Ekoube Ritha Carole, Mbono Betoko Calixthe, Ida Penda Jeanne Georgette, Mony Elimbi Patricia, Epee Iyawa, Hassanatou Edgar, Mandeng Ma Linwa Michael Ngenge, Budzi Gaelle, Ntsoli Kofane Claudia, Ekame Bulu Bianca Dicka, Sajida Misse Paul, Koki Ndombo Daniele-Christiane, Kedy Mangamba Koum |
author_sort | Charlotte, Eposse Ekoube |
collection | PubMed |
description | BACKGROUND: Sickle cell disease (SCD) is a chronic disease with many complications among which is growth retardation. Here, we described the growth and nutritional status patterns of children with SCD and adolescents living in Douala, Cameroon. METHODS: This cross-sectional study took place at the sickle cell treatment center of Douala Laquintinie Hospital from November 2015 to April 2016. The sociodemographic and anthropometric information of each SCD patient was determined, and then used for computing z-score indexes (weight for age, weight for height, body mass index for height, and height for age). The different indexes were used to determine the prevalence of malnutrition forms (stunting, wasting, underweight, and overweight/obesity) and compared to WHO standards by gender and age. RESULTS: A total of 208 children and adolescents participated in the study. The mean age was 8 years (±5) and the median age was 7 years. Males accounted for 53.4% of cases, giving a sex ratio of 1:1.1. The proportions of wasting, stunting, underweight, and overweight/obesity in the overall population were 7.1% (n = 15), 9.1% (n = 19), 3.6% (n = 5) and 3.3% (n = 7) respectively. In children under 5, wasting, stunting, underweight, and overweight/obesity were noted in 1.4% (n = 1), 9.5% (n = 7), 1.4% (n = 1), and 5.4% (n = 4) respectively. In patients aged 5 years and above, a proportion of 10.5% (n = 14) was wasted, 9.0% (n = 12) were stunted, 5.9% (n = 4) were underweight and 2.2% (n = 7) were overweight/obese. The growth curve of children under five in our study was superimposable to the WHO standard growth curve. In children older than 5 years, the left shift for stunting was more pronounced for boys compared to girls. CONCLUSION: Nine percent of children and adolescents with SCD are stunted. The growth deficit appeared to be higher in patients aged 5 years and above, more particularly in boys than girls. Overweight/obesity was uncommon in our series. More robust research designs and statistical analyses are needed to confirm or refute these findings. |
format | Online Article Text |
id | pubmed-9793582 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-97935822022-12-28 Describing the growth and nutritional status of sickle cell disease children and adolescents with reference to WHO growth standards in Cameroon Charlotte, Eposse Ekoube Ritha Carole, Mbono Betoko Calixthe, Ida Penda Jeanne Georgette, Mony Elimbi Patricia, Epee Iyawa, Hassanatou Edgar, Mandeng Ma Linwa Michael Ngenge, Budzi Gaelle, Ntsoli Kofane Claudia, Ekame Bulu Bianca Dicka, Sajida Misse Paul, Koki Ndombo Daniele-Christiane, Kedy Mangamba Koum BMC Nutr Research BACKGROUND: Sickle cell disease (SCD) is a chronic disease with many complications among which is growth retardation. Here, we described the growth and nutritional status patterns of children with SCD and adolescents living in Douala, Cameroon. METHODS: This cross-sectional study took place at the sickle cell treatment center of Douala Laquintinie Hospital from November 2015 to April 2016. The sociodemographic and anthropometric information of each SCD patient was determined, and then used for computing z-score indexes (weight for age, weight for height, body mass index for height, and height for age). The different indexes were used to determine the prevalence of malnutrition forms (stunting, wasting, underweight, and overweight/obesity) and compared to WHO standards by gender and age. RESULTS: A total of 208 children and adolescents participated in the study. The mean age was 8 years (±5) and the median age was 7 years. Males accounted for 53.4% of cases, giving a sex ratio of 1:1.1. The proportions of wasting, stunting, underweight, and overweight/obesity in the overall population were 7.1% (n = 15), 9.1% (n = 19), 3.6% (n = 5) and 3.3% (n = 7) respectively. In children under 5, wasting, stunting, underweight, and overweight/obesity were noted in 1.4% (n = 1), 9.5% (n = 7), 1.4% (n = 1), and 5.4% (n = 4) respectively. In patients aged 5 years and above, a proportion of 10.5% (n = 14) was wasted, 9.0% (n = 12) were stunted, 5.9% (n = 4) were underweight and 2.2% (n = 7) were overweight/obese. The growth curve of children under five in our study was superimposable to the WHO standard growth curve. In children older than 5 years, the left shift for stunting was more pronounced for boys compared to girls. CONCLUSION: Nine percent of children and adolescents with SCD are stunted. The growth deficit appeared to be higher in patients aged 5 years and above, more particularly in boys than girls. Overweight/obesity was uncommon in our series. More robust research designs and statistical analyses are needed to confirm or refute these findings. BioMed Central 2022-12-27 /pmc/articles/PMC9793582/ /pubmed/36575492 http://dx.doi.org/10.1186/s40795-022-00650-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Charlotte, Eposse Ekoube Ritha Carole, Mbono Betoko Calixthe, Ida Penda Jeanne Georgette, Mony Elimbi Patricia, Epee Iyawa, Hassanatou Edgar, Mandeng Ma Linwa Michael Ngenge, Budzi Gaelle, Ntsoli Kofane Claudia, Ekame Bulu Bianca Dicka, Sajida Misse Paul, Koki Ndombo Daniele-Christiane, Kedy Mangamba Koum Describing the growth and nutritional status of sickle cell disease children and adolescents with reference to WHO growth standards in Cameroon |
title | Describing the growth and nutritional status of sickle cell disease children and adolescents with reference to WHO growth standards in Cameroon |
title_full | Describing the growth and nutritional status of sickle cell disease children and adolescents with reference to WHO growth standards in Cameroon |
title_fullStr | Describing the growth and nutritional status of sickle cell disease children and adolescents with reference to WHO growth standards in Cameroon |
title_full_unstemmed | Describing the growth and nutritional status of sickle cell disease children and adolescents with reference to WHO growth standards in Cameroon |
title_short | Describing the growth and nutritional status of sickle cell disease children and adolescents with reference to WHO growth standards in Cameroon |
title_sort | describing the growth and nutritional status of sickle cell disease children and adolescents with reference to who growth standards in cameroon |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793582/ https://www.ncbi.nlm.nih.gov/pubmed/36575492 http://dx.doi.org/10.1186/s40795-022-00650-4 |
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