Quercetin alleviates cyclophosphamide-induced premature ovarian insufficiency in mice by reducing mitochondrial oxidative stress and pyroptosis in granulosa cells

BACKGROUND: Exposure to cyclophosphamide (CTX) induces premature ovarian insufficiency (POI). Quercetin is a natural flavonoid that exhibits anti-inflammatory and antioxidant properties, and its antioxidant activity is correlated with POI. However, the mechanism underlying its protective role in CTX...

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Detalles Bibliográficos
Autores principales: Chen, Yun, Zhao, Ying, Miao, Chenyun, Yang, Liuqing, Wang, Ruye, Chen, Bixia, Zhang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793602/
https://www.ncbi.nlm.nih.gov/pubmed/36572950
http://dx.doi.org/10.1186/s13048-022-01080-3

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