Cargando…

Protective effects of Gypenoside XVII against cerebral ischemia/reperfusion injury via SIRT1-FOXO3A- and Hif1a-BNIP3-mediated mitochondrial autophagy

BACKGROUND: Mitochondrial autophagy maintains mitochondrial function and cellular homeostasis and plays a critical role in the pathological process of cerebral ischemia/reperfusion injury (CIRI). Whether Gypenoside XVII (GP17) has regulatory effects on mitochondrial autophagy against CIRI remains un...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Weijie, Zhu, Ting, Zhang, Shuxia, Sun, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793669/
https://www.ncbi.nlm.nih.gov/pubmed/36572901
http://dx.doi.org/10.1186/s12967-022-03830-9