Preventing Retinal Detachment: Where are We? Implications from Stickler Syndrome

Stickler syndrome, a rare inherited disease, carries a lifetime risk of rhegmatogenous retinal detachment (RRD) of up to 65%, higher than any other predisposing condition known. Both syndromic and non-syndromic eyes suffer RRD predominately from the same pathogenesis, vitreous tractional tears in th...

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Autores principales: Morris, Robert E, Kuhn, Ferenc, Sipos, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793794/
https://www.ncbi.nlm.nih.gov/pubmed/36583093
http://dx.doi.org/10.2147/OPTH.S388631
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author Morris, Robert E
Kuhn, Ferenc
Sipos, Timothy
author_facet Morris, Robert E
Kuhn, Ferenc
Sipos, Timothy
author_sort Morris, Robert E
collection PubMed
description Stickler syndrome, a rare inherited disease, carries a lifetime risk of rhegmatogenous retinal detachment (RRD) of up to 65%, higher than any other predisposing condition known. Both syndromic and non-syndromic eyes suffer RRD predominately from the same pathogenesis, vitreous tractional tears in the peripheral retina. Consequently, extraordinary publications in 2021–2022, each reporting successful prevention of RRD in Stickler syndrome, using 360-degree (encircling) laser retinopexy, provide the first strong evidence upon which similar prophylaxis in non-syndromic eyes at high risk of RRD from peripheral retinal tears can confidently go forward.
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spelling pubmed-97937942022-12-28 Preventing Retinal Detachment: Where are We? Implications from Stickler Syndrome Morris, Robert E Kuhn, Ferenc Sipos, Timothy Clin Ophthalmol Perspectives Stickler syndrome, a rare inherited disease, carries a lifetime risk of rhegmatogenous retinal detachment (RRD) of up to 65%, higher than any other predisposing condition known. Both syndromic and non-syndromic eyes suffer RRD predominately from the same pathogenesis, vitreous tractional tears in the peripheral retina. Consequently, extraordinary publications in 2021–2022, each reporting successful prevention of RRD in Stickler syndrome, using 360-degree (encircling) laser retinopexy, provide the first strong evidence upon which similar prophylaxis in non-syndromic eyes at high risk of RRD from peripheral retinal tears can confidently go forward. Dove 2022-12-23 /pmc/articles/PMC9793794/ /pubmed/36583093 http://dx.doi.org/10.2147/OPTH.S388631 Text en © 2022 Morris et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Perspectives
Morris, Robert E
Kuhn, Ferenc
Sipos, Timothy
Preventing Retinal Detachment: Where are We? Implications from Stickler Syndrome
title Preventing Retinal Detachment: Where are We? Implications from Stickler Syndrome
title_full Preventing Retinal Detachment: Where are We? Implications from Stickler Syndrome
title_fullStr Preventing Retinal Detachment: Where are We? Implications from Stickler Syndrome
title_full_unstemmed Preventing Retinal Detachment: Where are We? Implications from Stickler Syndrome
title_short Preventing Retinal Detachment: Where are We? Implications from Stickler Syndrome
title_sort preventing retinal detachment: where are we? implications from stickler syndrome
topic Perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793794/
https://www.ncbi.nlm.nih.gov/pubmed/36583093
http://dx.doi.org/10.2147/OPTH.S388631
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