Cargando…

Network pharmacology approach and experimental verification of Dan-Shen Decoction in the treatment of ischemic heart disease

CONTEXT: Dan-Shen Decoction, which is composed of Danshen, Tanxiang and Sharen, has a good therapeutic effect on ischemic heart disease (IHD). However, systematic research on the exact mechanism of action of Dan-Shen Decoction is still lacking. The anti-IHD effect of Dan-Shen Decoction was examined...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gong, Difei, Yuan, Tianyi, Wang, Ranran, Sun, Shuchan, Dawuti, Awaguli, Wang, Shoubao, Du, Guanhua, Fang, Lianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793910/ https://www.ncbi.nlm.nih.gov/pubmed/36546685 http://dx.doi.org/10.1080/13880209.2022.2152059

Ejemplares similares

Systems Pharmacology-Based Strategy to Investigate Pharmacological Mechanisms of Total Flavonoids in Dracocephalum moldavica on Chronic Heart Failure
por: Dawuti, Awaguli, et al.
Publicado: (2022)

Puerarin-V Improve Mitochondrial Respiration and Cardiac Function in a Rat Model of Diabetic Cardiomyopathy via Inhibiting Pyroptosis Pathway through P2X7 Receptors
por: Sun, Shuchan, et al.
Publicado: (2022)

Puerarin Inhibits NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis via P2X7 Receptor in Cardiomyocytes and Macrophages
por: Sun, Shuchan, et al.
Publicado: (2023)

Insights into Endothelin Receptors in Pulmonary Hypertension
por: Liu, Ruiqi, et al.
Publicado: (2023)

Mechanism of Sanhua Decoction in the Treatment of Ischemic Stroke Based on Network Pharmacology Methods and Experimental Verification
por: YingHuang,, et al.
Publicado: (2022)

Network Pharmacology Analysis and Experimental Verification Strategies Reveal the Action Mechanism of Danshen Decoction in Treating Ischemic Cardiomyopathy
por: Liu, Mengnan, et al.
Publicado: (2022)

Network Pharmacology Analysis of ZiShenWan for Diabetic Nephropathy and Experimental Verification of Its Anti-Inflammatory Mechanism
por: Guo, Xiaoyuan, et al.
Publicado: (2021)

Deciphering potential pharmacological mechanism of Sha-Shen-Mai-Dong decoction on primary Sjogren’s syndrome
por: Jiang, Yuepeng, et al.
Publicado: (2021)

Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis
por: Hong, Mengyun, et al.
Publicado: (2022)

Network Pharmacology and Experimental Verification Strategies to Illustrate the Mechanism of Jian-Pi-Yi-Shen Formula in Suppressing Epithelial–Mesenchymal Transition
por: Zhao, Yuan, et al.
Publicado: (2022)

Network pharmacology and in vitro experimental verification to explore the mechanism of Sanhua decoction in the treatment of ischaemic stroke
por: Zhang, Wei, et al.
Publicado: (2022)

Exploring the Potential Mechanism of Tang-Shen-Ning Decoction against Diabetic Nephropathy Based on the Combination of Network Pharmacology and Experimental Validation
por: Liang, Jiajun, et al.
Publicado: (2021)

Network Pharmacology Prediction and Pharmacological Verification Mechanism of Yeju Jiangya Decoction on Hypertension
por: Wang, Ting, et al.
Publicado: (2021)

Network pharmacology and experimental verification of the potential mechanism of Er-Xian decoction in aplastic anemia
por: Ye, Mei, et al.
Publicado: (2023)

Study on the Anti-demyelination Mechanism of Bu-Shen-Yi-Sui Capsule in the Central Nervous System Based on Network Pharmacology and Experimental Verification
por: Zha, Zheng, et al.
Publicado: (2022)

A Network Pharmacology Approach to Uncover the Mechanisms of Shen-Qi-Di-Huang Decoction against Diabetic Nephropathy
por: Di, Sha, et al.
Publicado: (2018)

Analysis of the Anti-Tumour Effect of Xuefu Zhuyu Decoction Based on Network Pharmacology and Experimental Verification in Drosophila
por: Wang, Sitong, et al.
Publicado: (2022)

Exploring the role and mechanism of Fuzi decoction in the treatment of osteoporosis by integrating network pharmacology and experimental verification
por: Li, Fudong, et al.
Publicado: (2023)

Identification of the Active Constituents and Significant Pathways of Shen-qi-Yi-zhu Decoction on Antigastric Cancer: A Network Pharmacology Research and Experimental Validation
por: Zeng, Shuhong, et al.
Publicado: (2021)

Investigation on the mechanism of Shaoyao-Gancao Decoction in the treatment of gastric carcinoma based on network pharmacology and experimental verification
por: Zhou, Xin, et al.
Publicado: (2023)

Exploring the comorbidity mechanisms between asthma and idiopathic pulmonary fibrosis and the pharmacological mechanisms of Bu-Shen-Yi-Qi decoction therapy via network pharmacology
por: Zhong, Yuanyuan, et al.
Publicado: (2022)

Cardioprotective Effects of Puerarin-V on Isoproterenol-Induced Myocardial Infarction Mice Is Associated with Regulation of PPAR-Υ/NF-κB Pathway
por: Li, Xuguang, et al.
Publicado: (2018)

Network pharmacology, molecular docking, and experimental verification reveal the mechanism of San-Huang decoction in treating acute kidney injury
por: Liu, Jiahui, et al.
Publicado: (2023)

The mechanisms of Huangqi Guizhi Wuwu decoction in treating ischaemic stroke based on network pharmacology and experiment verification
por: Liao, Weiguo, et al.
Publicado: (2023)

Identification of Active Compounds and Mechanism of Huangtu Decoction for the Treatment of Ulcerative Colitis by Network Pharmacology Combined with Experimental Verification
por: Chen, Wenwen, et al.
Publicado: (2021)

Exploring the Mechanisms of Modified Bu-Shen-Yi-Qi Decoction for COPD-Related Osteoporosis Therapy via Transcriptomics and Network Pharmacology Approach
por: Zhong, Yuanyuan, et al.
Publicado: (2023)

Decoding the Mechanism of Shen Qi Sha Bai Decoction in Treating Acute Myeloid Leukemia Based on Network Pharmacology and Molecular Docking
por: Jia, Guanfei, et al.
Publicado: (2021)

Potential effect of Maxing Shigan decoction against coronavirus disease 2019 (COVID-19) revealed by network pharmacology and experimental verification
por: Li, Yuan, et al.
Publicado: (2021)

Chemical characterization and metabolic profiling of Xiao-Er-An-Shen Decoction by UPLC-QTOF/MS
por: Yang, Ruipei, et al.
Publicado: (2023)

Potential mechanism of Taohong Siwu Decoction in uterine fibroid treatment based on integrated strategy of network pharmacology and experimental verification
por: Shi, Shasha, et al.
Publicado: (2023)

Exploration of the Potential Mechanism of Tao Hong Si Wu Decoction for the Treatment of Breast Cancer Based on Network Pharmacology and In Vitro Experimental Verification
por: Huang, Shi, et al.
Publicado: (2021)

Network Pharmacology Combined with Molecular Docking and Experimental Verification Reveals the Bioactive Components and Potential Targets of Danlong Dingchuan Decoction against Asthma
por: Xue, Beibei, et al.
Publicado: (2022)

Systems Pharmacology and Verification of ShenFuHuang Formula in Zebrafish Model Reveal Multi-Scale Treatment Strategy for Septic Syndrome in COVID-19
por: Liu, Tengwen, et al.
Publicado: (2020)

Pharmacological Mechanism of Shen Huang Chong Ji for Treating Alzheimer's Disease Based on Network Pharmacology and Experimental Validation
por: Tang, Lei, et al.
Publicado: (2022)

Systems Pharmacology Dissection of Traditional Chinese Medicine Wen-Dan Decoction for Treatment of Cardiovascular Diseases
por: Lan, Tao-Hua, et al.
Publicado: (2018)

Network Pharmacology Analysis and Machine-Learning Models Confirmed the Ability of YiShen HuoXue Decoction to Alleviate Renal Fibrosis by Inhibiting Pyroptosis
por: Feng, MinChao, et al.
Publicado: (2023)

Potential Mechanism of Dingji Fumai Decoction Against Atrial Fibrillation Based on Network Pharmacology, Molecular Docking, and Experimental Verification Integration Strategy
por: Liang, Yi, et al.
Publicado: (2021)

Prediction of the Mechanism of Shaoyao Gancao Decoction in the Treatment of Alopecia Areata by Network Pharmacology and Its Preliminary Verification Study
por: Lv, Shuying, et al.
Publicado: (2022)

Exploration of the mechanism of luteolin against ischemic stroke based on network pharmacology, molecular docking and experimental verification
por: Dong, Rui, et al.
Publicado: (2021)

Protective Effects and Mechanisms of Yinchen Linggui Zhugan Decoction in HFD-Induced Nonalcoholic Fatty Liver Disease Rats Based on Network Pharmacology and Experimental Verification
por: Jiang, Hui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qn7ifh0p6thi0kmdtgk7k6ar67