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The Influence of Carboxytherapy on Scar Reduction

INTRODUCTION: Although it is not a new method, a carboxytherapy, which is based on intradermal or subcutaneous administration of controlled doses of CO2, is gaining more and more recognition among aesthetic medicine doctors, dermatologists and cosmetologists around the world. The consequence of appl...

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Autores principales: Stolecka-Warzecha, Anna, Chmielewski, Łukasz, Deda, Anna, Śmich, Aleksandra, Lebiedowska, Agata, Wilczyński, Sławomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793937/
https://www.ncbi.nlm.nih.gov/pubmed/36582848
http://dx.doi.org/10.2147/CCID.S389380
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author Stolecka-Warzecha, Anna
Chmielewski, Łukasz
Deda, Anna
Śmich, Aleksandra
Lebiedowska, Agata
Wilczyński, Sławomir
author_facet Stolecka-Warzecha, Anna
Chmielewski, Łukasz
Deda, Anna
Śmich, Aleksandra
Lebiedowska, Agata
Wilczyński, Sławomir
author_sort Stolecka-Warzecha, Anna
collection PubMed
description INTRODUCTION: Although it is not a new method, a carboxytherapy, which is based on intradermal or subcutaneous administration of controlled doses of CO2, is gaining more and more recognition among aesthetic medicine doctors, dermatologists and cosmetologists around the world. The consequence of applying carbon dioxide directly into tissues is associated with an immediate expansion of blood vessels, improvement of local blood supply, and, thus, tissue metabolism. It does also support natural regenerative processes. Oxygen and growth factors released from blood, within the area which undergoes treatment, stimulate fibroblasts to produce collagen and formation of new blood vessels also known as neovascularization. In addition to biochemical mechanisms, CO2 injection into the dermis or subcutaneous tissue leads to a mechanical effect exerted by pressure and flow of CO2 which is injected. It is of particular importance in scar treatments. METHODS: Twelve mature scars were subjected to the carboxytherapy which was performed in people aged 23–45 years. A small amount of heated, medical CO2 was injected till the moment a scar turns white. The applied flow rate equalled 100 mL/min (cc/min). Before and after a series of four treatments, the level of hydration, elasticity and colour of the skin were measured. A structured-light 3D scanner was used to determine an exact morphology of the examined scars. The 3D scanning device is seen as a sensitive and precise method of qualitative and quantitative assessment of a morphology of scars. RESULTS: The results of the measurements performed showed a reduction in the surface of the analyzed changes, as well as proved the ability of CO2 to rebuild collagen fibres. The decrease in value of parameters, which have been obtained thanks to the kutometric examination, indicates softening and loosening of connective tissue. It does confirm the effectiveness of carboxytherapy.
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spelling pubmed-97939372022-12-28 The Influence of Carboxytherapy on Scar Reduction Stolecka-Warzecha, Anna Chmielewski, Łukasz Deda, Anna Śmich, Aleksandra Lebiedowska, Agata Wilczyński, Sławomir Clin Cosmet Investig Dermatol Original Research INTRODUCTION: Although it is not a new method, a carboxytherapy, which is based on intradermal or subcutaneous administration of controlled doses of CO2, is gaining more and more recognition among aesthetic medicine doctors, dermatologists and cosmetologists around the world. The consequence of applying carbon dioxide directly into tissues is associated with an immediate expansion of blood vessels, improvement of local blood supply, and, thus, tissue metabolism. It does also support natural regenerative processes. Oxygen and growth factors released from blood, within the area which undergoes treatment, stimulate fibroblasts to produce collagen and formation of new blood vessels also known as neovascularization. In addition to biochemical mechanisms, CO2 injection into the dermis or subcutaneous tissue leads to a mechanical effect exerted by pressure and flow of CO2 which is injected. It is of particular importance in scar treatments. METHODS: Twelve mature scars were subjected to the carboxytherapy which was performed in people aged 23–45 years. A small amount of heated, medical CO2 was injected till the moment a scar turns white. The applied flow rate equalled 100 mL/min (cc/min). Before and after a series of four treatments, the level of hydration, elasticity and colour of the skin were measured. A structured-light 3D scanner was used to determine an exact morphology of the examined scars. The 3D scanning device is seen as a sensitive and precise method of qualitative and quantitative assessment of a morphology of scars. RESULTS: The results of the measurements performed showed a reduction in the surface of the analyzed changes, as well as proved the ability of CO2 to rebuild collagen fibres. The decrease in value of parameters, which have been obtained thanks to the kutometric examination, indicates softening and loosening of connective tissue. It does confirm the effectiveness of carboxytherapy. Dove 2022-12-23 /pmc/articles/PMC9793937/ /pubmed/36582848 http://dx.doi.org/10.2147/CCID.S389380 Text en © 2022 Stolecka-Warzecha et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Stolecka-Warzecha, Anna
Chmielewski, Łukasz
Deda, Anna
Śmich, Aleksandra
Lebiedowska, Agata
Wilczyński, Sławomir
The Influence of Carboxytherapy on Scar Reduction
title The Influence of Carboxytherapy on Scar Reduction
title_full The Influence of Carboxytherapy on Scar Reduction
title_fullStr The Influence of Carboxytherapy on Scar Reduction
title_full_unstemmed The Influence of Carboxytherapy on Scar Reduction
title_short The Influence of Carboxytherapy on Scar Reduction
title_sort influence of carboxytherapy on scar reduction
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793937/
https://www.ncbi.nlm.nih.gov/pubmed/36582848
http://dx.doi.org/10.2147/CCID.S389380
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