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Sequential control of myeloid cell proliferation and differentiation by cytokine receptor-based chimeric antigen receptors

As chimeric antigen receptor (CAR)-T cell therapy has been recently applied in clinics, controlling the fate of blood cells is increasingly important for curing blood disorders. In this study, we aim to construct proliferation-inducing and differentiation-inducing CARs (piCAR and diCAR) with two dif...

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Detalles Bibliográficos
Autores principales: Nakajima, Kyoko, Shen, Zhongchuzi, Miura, Masashi, Nakabayashi, Hideto, Kawahara, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794043/
https://www.ncbi.nlm.nih.gov/pubmed/36574389
http://dx.doi.org/10.1371/journal.pone.0279409