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PARP1 recruits DNA translocases to restrain DNA replication and facilitate DNA repair

Replication fork reversal which restrains DNA replication progression is an important protective mechanism in response to replication stress. PARP1 is recruited to stalled forks to restrain DNA replication. However, PARP1 has no helicase activity, and the mechanism through which PARP1 participates i...

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Detalles Bibliográficos
Autores principales: Ho, Yen-Chih, Ku, Chen-Syun, Tsai, Siang-Sheng, Shiu, Jia-Lin, Jiang, Yi-Zhen, Miriam, Hui Emmanuela, Zhang, Han-Wen, Chen, Yen-Tzu, Chiu, Wen-Tai, Chang, Song-Bin, Shen, Che-Hung, Myung, Kyungjae, Chi, Peter, Liaw, Hungjiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794062/
https://www.ncbi.nlm.nih.gov/pubmed/36512630
http://dx.doi.org/10.1371/journal.pgen.1010545

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