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Synthesis, antimicrobial and molecular docking study of structural analogues of 3-((5-(dimethylcarbamoyl)pyrrolidin-3-yl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The goal of the current work was to create structural analogues of a beta lactam antibiotic that might be possibly effective against bacterial resistant strains. FTIR, (1)H NMR, (13)C NMR, and CHNS analyses were used to perform the spectroscopic study on the compounds M(1–8). The effects of the afor...

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Detalles Bibliográficos
Autores principales: Khaliq, Saharish, Khan, Mohsin Abbas, Ahmad, Irshad, Ahmad, Imtiaz, Ahmed, Javed, Ullah, Farhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794083/
https://www.ncbi.nlm.nih.gov/pubmed/36574404
http://dx.doi.org/10.1371/journal.pone.0278684