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The independent risk factors for abnormal head computed tomography in patients with hepatic encephalopathy

It’s known that head computed tomography (CT) is used excessively to exclude intracranial hemorrhage in patients with hepatic encephalopathy (HE) in the emergency department. However, the independent risk factors for abnormal head CT in patients with HE have not been studied extensively to date. In...

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Autores principales: Basak, Bayram, Ersin, Aksay, Sefer, Ozgur, Gucluhan, Ucar, Sebnem, Sakar, Colak, Nese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794209/
https://www.ncbi.nlm.nih.gov/pubmed/36595845
http://dx.doi.org/10.1097/MD.0000000000032469
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author Basak, Bayram
Ersin, Aksay
Sefer, Ozgur
Gucluhan, Ucar
Sebnem, Sakar
Colak, Nese
author_facet Basak, Bayram
Ersin, Aksay
Sefer, Ozgur
Gucluhan, Ucar
Sebnem, Sakar
Colak, Nese
author_sort Basak, Bayram
collection PubMed
description It’s known that head computed tomography (CT) is used excessively to exclude intracranial hemorrhage in patients with hepatic encephalopathy (HE) in the emergency department. However, the independent risk factors for abnormal head CT in patients with HE have not been studied extensively to date. In this retrospective study, patients with an ammonia level of >90 U/L who were clinically considered HE and had head CT were included. The characteristics of patients with abnormal head CT and independent risk factors for abnormal CT were investigated. Three hundred seventy-eight patients were included in the study. CT findings of 18 (4.8%) of the patients were abnormal: 12 had intracranial hemorrhage, 1 had an ischemic stroke, and 5 had an intracranial mass. Intracranial hemorrhage (odds ratio [OR] 12.5), history of recent trauma (OR 23.4), history of active malignancy (OR 10.3), thrombocyte count <100.000/μL (OR 4.3), and international normalized ratio ≥1.5 (OR 3.2) were found to be independent risk factors for abnormal head CT. Head CT scan may be considered in patients with HE if any of the following are present: intracranial bleeding history, recent trauma history, active malignancy, platelet count <100,000/μL, and international normalized ratio >1.5.
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spelling pubmed-97942092022-12-28 The independent risk factors for abnormal head computed tomography in patients with hepatic encephalopathy Basak, Bayram Ersin, Aksay Sefer, Ozgur Gucluhan, Ucar Sebnem, Sakar Colak, Nese Medicine (Baltimore) 3900 It’s known that head computed tomography (CT) is used excessively to exclude intracranial hemorrhage in patients with hepatic encephalopathy (HE) in the emergency department. However, the independent risk factors for abnormal head CT in patients with HE have not been studied extensively to date. In this retrospective study, patients with an ammonia level of >90 U/L who were clinically considered HE and had head CT were included. The characteristics of patients with abnormal head CT and independent risk factors for abnormal CT were investigated. Three hundred seventy-eight patients were included in the study. CT findings of 18 (4.8%) of the patients were abnormal: 12 had intracranial hemorrhage, 1 had an ischemic stroke, and 5 had an intracranial mass. Intracranial hemorrhage (odds ratio [OR] 12.5), history of recent trauma (OR 23.4), history of active malignancy (OR 10.3), thrombocyte count <100.000/μL (OR 4.3), and international normalized ratio ≥1.5 (OR 3.2) were found to be independent risk factors for abnormal head CT. Head CT scan may be considered in patients with HE if any of the following are present: intracranial bleeding history, recent trauma history, active malignancy, platelet count <100,000/μL, and international normalized ratio >1.5. Lippincott Williams & Wilkins 2022-12-23 /pmc/articles/PMC9794209/ /pubmed/36595845 http://dx.doi.org/10.1097/MD.0000000000032469 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 3900
Basak, Bayram
Ersin, Aksay
Sefer, Ozgur
Gucluhan, Ucar
Sebnem, Sakar
Colak, Nese
The independent risk factors for abnormal head computed tomography in patients with hepatic encephalopathy
title The independent risk factors for abnormal head computed tomography in patients with hepatic encephalopathy
title_full The independent risk factors for abnormal head computed tomography in patients with hepatic encephalopathy
title_fullStr The independent risk factors for abnormal head computed tomography in patients with hepatic encephalopathy
title_full_unstemmed The independent risk factors for abnormal head computed tomography in patients with hepatic encephalopathy
title_short The independent risk factors for abnormal head computed tomography in patients with hepatic encephalopathy
title_sort independent risk factors for abnormal head computed tomography in patients with hepatic encephalopathy
topic 3900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794209/
https://www.ncbi.nlm.nih.gov/pubmed/36595845
http://dx.doi.org/10.1097/MD.0000000000032469
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