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The role of vitamin A and zinc supplementation in pediatric pneumonia: A protocol for systematic review and network meta-analysis

There is still controversy regarding the role of zinc and vitamin A supplementation in pediatric pneumonia. Therefore, we designed a systematic review and network meta-analysis to incorporate the available evidence to determine the role of vitamin A and zinc in pediatric pneumonia. METHODS: From the...

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Autores principales: Shi, Yu, Lei, Qihong, Liu, Hongxia, Han, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794312/
https://www.ncbi.nlm.nih.gov/pubmed/36595780
http://dx.doi.org/10.1097/MD.0000000000032183
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author Shi, Yu
Lei, Qihong
Liu, Hongxia
Han, Qing
author_facet Shi, Yu
Lei, Qihong
Liu, Hongxia
Han, Qing
author_sort Shi, Yu
collection PubMed
description There is still controversy regarding the role of zinc and vitamin A supplementation in pediatric pneumonia. Therefore, we designed a systematic review and network meta-analysis to incorporate the available evidence to determine the role of vitamin A and zinc in pediatric pneumonia. METHODS: From the inception to December 31, 2022, the Web of Science, EMBASE, Medicine, the Cochrane Central Register of Controlled Trials and Cochrane Library electronic databases were searched using the key phrases “pneumonia,” “pediatric,” “zinc,” “vitamin A,” and “cohort” for all relevant studies. Cohort studies assessing the efficacy and safety of zinc and/or vitamin A supplementation in children with pneumonia will be included for quantitative or qualitative analysis. Non-cohort studies and studies that do not meet the inclusion criteria will be excluded. Outcome measures include reduction in duration of pneumonia, adverse drug events, length of hospital stay, amount of antibiotics used, and radiological parameters. The primary outcome is the degree of reduction in the duration of pneumonia. RESULTS: This Bayesian network meta-analysis will be conducted in accordance with the PRISMA extension statement, which is used to report systematic reviews that incorporated a meta-analysis of medical intervention networks.
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spelling pubmed-97943122022-12-28 The role of vitamin A and zinc supplementation in pediatric pneumonia: A protocol for systematic review and network meta-analysis Shi, Yu Lei, Qihong Liu, Hongxia Han, Qing Medicine (Baltimore) 6700 There is still controversy regarding the role of zinc and vitamin A supplementation in pediatric pneumonia. Therefore, we designed a systematic review and network meta-analysis to incorporate the available evidence to determine the role of vitamin A and zinc in pediatric pneumonia. METHODS: From the inception to December 31, 2022, the Web of Science, EMBASE, Medicine, the Cochrane Central Register of Controlled Trials and Cochrane Library electronic databases were searched using the key phrases “pneumonia,” “pediatric,” “zinc,” “vitamin A,” and “cohort” for all relevant studies. Cohort studies assessing the efficacy and safety of zinc and/or vitamin A supplementation in children with pneumonia will be included for quantitative or qualitative analysis. Non-cohort studies and studies that do not meet the inclusion criteria will be excluded. Outcome measures include reduction in duration of pneumonia, adverse drug events, length of hospital stay, amount of antibiotics used, and radiological parameters. The primary outcome is the degree of reduction in the duration of pneumonia. RESULTS: This Bayesian network meta-analysis will be conducted in accordance with the PRISMA extension statement, which is used to report systematic reviews that incorporated a meta-analysis of medical intervention networks. Lippincott Williams & Wilkins 2022-12-23 /pmc/articles/PMC9794312/ /pubmed/36595780 http://dx.doi.org/10.1097/MD.0000000000032183 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 6700
Shi, Yu
Lei, Qihong
Liu, Hongxia
Han, Qing
The role of vitamin A and zinc supplementation in pediatric pneumonia: A protocol for systematic review and network meta-analysis
title The role of vitamin A and zinc supplementation in pediatric pneumonia: A protocol for systematic review and network meta-analysis
title_full The role of vitamin A and zinc supplementation in pediatric pneumonia: A protocol for systematic review and network meta-analysis
title_fullStr The role of vitamin A and zinc supplementation in pediatric pneumonia: A protocol for systematic review and network meta-analysis
title_full_unstemmed The role of vitamin A and zinc supplementation in pediatric pneumonia: A protocol for systematic review and network meta-analysis
title_short The role of vitamin A and zinc supplementation in pediatric pneumonia: A protocol for systematic review and network meta-analysis
title_sort role of vitamin a and zinc supplementation in pediatric pneumonia: a protocol for systematic review and network meta-analysis
topic 6700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794312/
https://www.ncbi.nlm.nih.gov/pubmed/36595780
http://dx.doi.org/10.1097/MD.0000000000032183
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