Breast Cancer Metastasis to the Gastrointestinal Tract With Unusual Endoscopic and Histologic Presentations

The gastrointestinal (GI) tract is an infrequent site of breast cancer metastasis, but it often poses a diagnostic challenge when it occurs. The symptoms of GI metastases are often nonspecific, and the endoscopic manifestations are variable, requiring tissue biopsies for histologic examination. We r...

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Autores principales: Kimchy, Alexandra V., Umoren, Mfonsio D., Rosenberg, Jessica J., Ilagan, Charmaine, Nithagon, Pichayut, Shafa, Shervin, Jennings, Joseph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794355/
https://www.ncbi.nlm.nih.gov/pubmed/36600790
http://dx.doi.org/10.14309/crj.0000000000000938
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author Kimchy, Alexandra V.
Umoren, Mfonsio D.
Rosenberg, Jessica J.
Ilagan, Charmaine
Nithagon, Pichayut
Shafa, Shervin
Jennings, Joseph J.
author_facet Kimchy, Alexandra V.
Umoren, Mfonsio D.
Rosenberg, Jessica J.
Ilagan, Charmaine
Nithagon, Pichayut
Shafa, Shervin
Jennings, Joseph J.
author_sort Kimchy, Alexandra V.
collection PubMed
description The gastrointestinal (GI) tract is an infrequent site of breast cancer metastasis, but it often poses a diagnostic challenge when it occurs. The symptoms of GI metastases are often nonspecific, and the endoscopic manifestations are variable, requiring tissue biopsies for histologic examination. We report 2 cases of breast cancer metastasizing to the GI tract: a case of human epidermal growth factor receptor 2-positive invasive ductal carcinoma that metastasized to the stomach, a rare location for this histologic subtype, and another case of invasive lobular cell carcinoma that metastasized to the colon with unusual findings of mucosal pallor and edema on colonoscopy.
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spelling pubmed-97943552023-01-03 Breast Cancer Metastasis to the Gastrointestinal Tract With Unusual Endoscopic and Histologic Presentations Kimchy, Alexandra V. Umoren, Mfonsio D. Rosenberg, Jessica J. Ilagan, Charmaine Nithagon, Pichayut Shafa, Shervin Jennings, Joseph J. ACG Case Rep J Case Report The gastrointestinal (GI) tract is an infrequent site of breast cancer metastasis, but it often poses a diagnostic challenge when it occurs. The symptoms of GI metastases are often nonspecific, and the endoscopic manifestations are variable, requiring tissue biopsies for histologic examination. We report 2 cases of breast cancer metastasizing to the GI tract: a case of human epidermal growth factor receptor 2-positive invasive ductal carcinoma that metastasized to the stomach, a rare location for this histologic subtype, and another case of invasive lobular cell carcinoma that metastasized to the colon with unusual findings of mucosal pallor and edema on colonoscopy. Wolters Kluwer 2022-12-26 /pmc/articles/PMC9794355/ /pubmed/36600790 http://dx.doi.org/10.14309/crj.0000000000000938 Text en © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Kimchy, Alexandra V.
Umoren, Mfonsio D.
Rosenberg, Jessica J.
Ilagan, Charmaine
Nithagon, Pichayut
Shafa, Shervin
Jennings, Joseph J.
Breast Cancer Metastasis to the Gastrointestinal Tract With Unusual Endoscopic and Histologic Presentations
title Breast Cancer Metastasis to the Gastrointestinal Tract With Unusual Endoscopic and Histologic Presentations
title_full Breast Cancer Metastasis to the Gastrointestinal Tract With Unusual Endoscopic and Histologic Presentations
title_fullStr Breast Cancer Metastasis to the Gastrointestinal Tract With Unusual Endoscopic and Histologic Presentations
title_full_unstemmed Breast Cancer Metastasis to the Gastrointestinal Tract With Unusual Endoscopic and Histologic Presentations
title_short Breast Cancer Metastasis to the Gastrointestinal Tract With Unusual Endoscopic and Histologic Presentations
title_sort breast cancer metastasis to the gastrointestinal tract with unusual endoscopic and histologic presentations
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794355/
https://www.ncbi.nlm.nih.gov/pubmed/36600790
http://dx.doi.org/10.14309/crj.0000000000000938
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