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Chemotherapy promotes astrocytic response to Aβ deposition, but not Aβ levels, in a mouse model of amyloid and APOE

Many cancer survivors experience cancer-related cognitive impairment (CRCI), which is characterized by problems of attention, working memory, and executive function following chemotherapy and/or hormonal treatment. APOE4, the strongest genetic risk factor for Alzheimer’s Disease (AD), is also a risk...

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Detalles Bibliográficos
Autores principales: Ng, Christi Anne S., Biran, Lucas P., Galvano, Elena, Mandelblatt, Jeanne, Vicini, Stefano, Rebeck, G. William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794416/
https://www.ncbi.nlm.nih.gov/pubmed/36336241
http://dx.doi.org/10.1016/j.nbd.2022.105915