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The NLRP3 Genetic Variant (rs10754555) Reduces the Risk of Adverse Outcome in Middle-Aged Patients with Chronic Coronary Syndrome

BACKGROUND: Inflammation is central in development of cardiovascular disease (CVD). Aberrant function of the Nod-Like Receptor Protein 3 (NLRP3) inflammasome, a central mediator in the proinflammatory response, has been associated with atherosclerosis. The influence of genetic determinants on this i...

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Detalles Bibliográficos
Autores principales:	Opstad, Trine B., Nordeng, Jostein, Pettersen, Alf-Aage R., Åkra, Sissel, Bratseth, Vibeke, Zaidi, Hani, Helseth, Ragnhild, Solheim, Svein, Seljeflot, Ingebjørg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794420/ https://www.ncbi.nlm.nih.gov/pubmed/36582742 http://dx.doi.org/10.1155/2022/2366695

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