Pneumolysin promotes host cell necroptosis and bacterial competence during pneumococcal meningitis as shown by whole-animal dual RNA-seq

Pneumolysin is a major virulence factor of Streptococcus pneumoniae that plays a key role in interaction with the host during invasive disease. How pneumolysin influences these dynamics between host and pathogen interaction during early phase of central nervous system infection in pneumococcal menin...

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Detalles Bibliográficos
Autores principales: Jim, Kin Ki, Aprianto, Rieza, Koning, Rutger, Domenech, Arnau, Kurushima, Jun, van de Beek, Diederik, Vandenbroucke-Grauls, Christina M.J.E., Bitter, Wilbert, Veening, Jan-Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794515/
https://www.ncbi.nlm.nih.gov/pubmed/36543127
http://dx.doi.org/10.1016/j.celrep.2022.111851

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