The splicing regulators TIA1 and TIAL1 are required for the expression of the DNA damage repair machinery during B cell lymphopoiesis

B cell lymphopoiesis requires dynamic modulation of the B cell transcriptome for timely coordination of somatic mutagenesis and DNA repair in progenitor B (pro-B) cells. Here, we show that, in pro-B cells, the RNA-binding proteins T cell intracellular antigen 1 (TIA1) and TIA1-like protein (TIAL1) a...

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Detalles Bibliográficos
Autores principales: Osma-Garcia, Ines C., Capitan-Sobrino, Dunja, Mouysset, Mailys, Aubert, Yann, Maloudi, Orlane, Turner, Martin, Diaz-Muñoz, Manuel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794549/
https://www.ncbi.nlm.nih.gov/pubmed/36543128
http://dx.doi.org/10.1016/j.celrep.2022.111869

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