Cargando…

Increased Caveolin-2 Expression in Brain Endothelial Cells Promotes Age-Related Neuroinflammation

Aging is a major risk factor for common neurodegenerative diseases. Although multiple molecular, cellular, structural, and functional changes occur in the brain during aging, the involvement of caveolin-2 (Cav-2) in brain ageing remains unknown. We investigated Cav-2 expression in brains of aged mic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Hyunju, Shin, Jung A, Lim, Jiwoo, Lee, Seulgi, Ahn, Jung-Hyuck, Kang, Jihee Lee, Choi, Youn-Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794556/ https://www.ncbi.nlm.nih.gov/pubmed/36572563 http://dx.doi.org/10.14348/molcells.2022.0045

Ejemplares similares

Protein-protein interaction between caveolin-1 and SHP-2 is dependent on the N-SH2 domain of SHP-2
por: Park, Hyunju, et al.
Publicado: (2015)

SHP-2 Binds to Caveolin-1 and Regulates Src Activity via Competitive Inhibition of CSK in Response to H(2)O(2) in Astrocytes
por: Jo, Ara, et al.
Publicado: (2014)

Traumatic brain injury enhances neuroinflammation and lesion volume in caveolin deficient mice
por: Niesman, Ingrid R, et al.
Publicado: (2014)

Necrotic cells influence migration and invasion of glioblastoma via NF-κB/AP-1-mediated IL-8 regulation
por: Ahn, So-Hee, et al.
Publicado: (2016)

The phosphodiesterase 10 inhibitor papaverine exerts anti-inflammatory and neuroprotective effects via the PKA signaling pathway in neuroinflammation and Parkinson’s disease mouse models
por: Lee, Yu-Young, et al.
Publicado: (2019)

Identification of a novel PARP4 gene promoter CpG locus associated with cisplatin chemoresistance
por: Sung, Hye Youn, et al.
Publicado: (2023)

Overexpression of caveolin-1 attenuates brain edema by inhibiting tight junction degradation
por: Choi, Kang-Ho, et al.
Publicado: (2016)

Csk-Induced Phosphorylation of Src at Tyrosine 530 is Essential for H(2)O(2)-Mediated Suppression of ERK1/2 in Human Umbilical Vein Endothelial Cells
por: Jeon, Bo Kyung, et al.
Publicado: (2015)

Increased phosphorylation of caveolin-1 in the spinal cord of irradiated rats
por: Kim, Heechul, et al.
Publicado: (2007)

Anti-Inflammatory and Neuroprotective Mechanisms of GTS-21, an α7 Nicotinic Acetylcholine Receptor Agonist, in Neuroinflammation and Parkinson’s Disease Mouse Models
por: Park, Jung-Eun, et al.
Publicado: (2022)

HMG-CoA Reductase Inhibitor Improves Endothelial Dysfunction in Spontaneous Hypertensive Rats Via Down-regulation of Caveolin-1 and Activation of Endothelial Nitric Oxide Synthase
por: Suh, Jung-Won, et al.
Publicado: (2010)

RIPK1 Regulates Microglial Activation in Lipopolysaccharide-Induced Neuroinflammation and MPTP-Induced Parkinson’s Disease Mouse Models
por: Kim, Do-Yeon, et al.
Publicado: (2023)

Endothelial caveolin at the crossroad of thrombo-inflammation coupling
por: ElAli, Ayman
Publicado: (2022)

Immunohistochemical study of caveolin-1 and -2 in the rat retina
por: Kim, Heechul, et al.
Publicado: (2006)

Effect of Renal Ischemia Reperfusion on Brain Neuroinflammation
por: Lee, Bina, et al.
Publicado: (2022)

Caveolin-1 is a primary determinant of endothelial stiffening associated with dyslipidemia, disturbed flow, and ageing
por: Le Master, Elizabeth, et al.
Publicado: (2022)

The TAM-family receptor Mer mediates production of HGF through the RhoA-dependent pathway in response to apoptotic cells
por: Park, Hyun-Jung, et al.
Publicado: (2012)

Promotion of human mesenchymal stem cell osteogenesis by PI3-kinase/Akt signaling, and the influence of caveolin-1/cholesterol homeostasis
por: Baker, Natasha, et al.
Publicado: (2015)

SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1
por: Fung, Karen Y., et al.
Publicado: (2017)

An Air Particulate Pollutant Induces Neuroinflammation and Neurodegeneration in Human Brain Models
por: Kang, You Jung, et al.
Publicado: (2021)

Caveolin-1 enhances brain metastasis of non-small cell lung cancer, potentially in association with the epithelial-mesenchymal transition marker SNAIL
por: Kim, Yeong-Jin, et al.
Publicado: (2019)

Elevation of ambient temperature is associated with an increased risk of herpes zoster: a time-series analysis
por: Choi, Yoon-Jung, et al.
Publicado: (2019)

Central metabolites and peripheral parameters associated neuroinflammation in fibromyalgia patients: A preliminary study
por: Jung, Ye-Ha, et al.
Publicado: (2023)

Loss of the Promyelocytic Leukemia Protein in Gastric Cancer: Implications for IP-10 Expression and Tumor-Infiltrating Lymphocytes
por: Kim, Hee Ja, et al.
Publicado: (2011)

Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration
por: Luo, Xiaoying, et al.
Publicado: (2018)

RhoA-Dependent HGF and c-Met Mediate Gas6-Induced Inhibition of Epithelial–Mesenchymal Transition, Migration, and Invasion of Lung Alveolar Epithelial Cells
por: Jung, Jihye, et al.
Publicado: (2019)

Effect of Necrosis on the miRNA-mRNA Regulatory Network in CRT-MG Human Astroglioma Cells
por: Ahn, So-Hee, et al.
Publicado: (2018)

Gas6 Prevents Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells via Production of PGE(2), PGD(2) and Their Receptors
por: Jung, Jihye, et al.
Publicado: (2019)

Caveolin‐1 deficiency induces premature senescence with mitochondrial dysfunction
por: Yu, Dong‐Min, et al.
Publicado: (2017)

Abnormal neuroinflammation in fibromyalgia and CRPS using [(11)C]-(R)-PK11195 PET
por: Seo, Seongho, et al.
Publicado: (2021)

Caveolae, Caveolins, Cavins, and Endothelial Cell Function: New Insights
por: Sowa, Grzegorz
Publicado: (2012)

Regulation of Cell Signaling and Function by Endothelial Caveolins: Implications in Disease
por: Sowa, Grzegorz
Publicado: (2012)

Caveolin-1 and Atherosclerosis: Regulation of LDLs Fate in Endothelial Cells
por: Puddu, Alessandra, et al.
Publicado: (2023)

STAT6 Signaling Mediates PPARγ Activation and Resolution of Acute Sterile Inflammation in Mice
por: Lee, Ye-JI, et al.
Publicado: (2021)

Identification and Characterization of MicroRNAs Associated with Somatic Copy Number Alterations in Cancer
por: Soh, Jihee, et al.
Publicado: (2018)

Perivascular Adipose Tissue Inhibits Endothelial Function of Rat Aortas via Caveolin-1
por: Lee, Michelle Hui-Hsin, et al.
Publicado: (2014)

Inhibitory Effects of Myricetin on Lipopolysaccharide-Induced Neuroinflammation
por: Jang, Jung-Hee, et al.
Publicado: (2020)

Periodontitis promotes bacterial extracellular vesicle-induced neuroinflammation in the brain and trigeminal ganglion
por: Ha, Jae Yeong, et al.
Publicado: (2023)

HIDTI: integration of heterogeneous information to predict drug-target interactions
por: Soh, Jihee, et al.
Publicado: (2022)

Super.FELT: supervised feature extraction learning using triplet loss for drug response prediction with multi-omics data
por: Park, Sejin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ddrgnt5r3m2mng18le4ej662v2