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3D tumor explant as a novel platform to investigate therapeutic pathways and predictive biomarkers in cancer patients

Immunotherapy with immune checkpoint inhibitors can induce durable clinical responses in different human malignancies but the number of responding patients remains globally modest. The limited therapeutic efficacy of ICI depends on multiple factors, among which the immune suppressive features of the...

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Detalles Bibliográficos
Autores principales:	Rodolfo, Monica, Huber, Veronica, Cossa, Mara, Gallino, Gianfrancesco, Leone, Biagio E., Vallacchi, Viviana, Rivoltini, Licia, Vergani, Elisabetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794575/ https://www.ncbi.nlm.nih.gov/pubmed/36591316 http://dx.doi.org/10.3389/fimmu.2022.1068091

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