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Elevated ITGA2 expression promotes collagen type I-induced clonogenic growth of intrahepatic cholangiocarcinoma

Intrahepatic cholangiocarcinoma (iCCA) arises along the peripheral bile ducts and is often accompanied by a tumor microenvironment (TME) high in extracellular matrices (ECMs). In this study, we aimed to evaluate whether an ECM-rich TME favors iCCA progression. We identified ITGA2, which encodes coll...

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Detalles Bibliográficos
Autores principales:	Rattanasinchai, Chotirat, Navasumrit, Panida, Ruchirawat, Mathuros
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794692/ https://www.ncbi.nlm.nih.gov/pubmed/36575207 http://dx.doi.org/10.1038/s41598-022-26747-1

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