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Electrostatic regulation of the cis- and trans-membrane interactions of synaptotagmin-1
Synaptotagmin-1 is a vesicular protein and Ca(2+) sensor for Ca(2+)-dependent exocytosis. Ca(2+) induces synaptotagmin-1 binding to its own vesicle membrane, called the cis-interaction, thus preventing the trans-interaction of synaptotagmin-1 to the plasma membrane. However, the electrostatic regula...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794720/ https://www.ncbi.nlm.nih.gov/pubmed/36575295 http://dx.doi.org/10.1038/s41598-022-26723-9 |