The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis

Ferroptosis is a type of regulated necrosis caused by unrestricted lipid peroxidation and subsequent plasma membrane rupture. However, the lipid remodeling mechanism that determines sensitivity to ferroptosis remains poorly understood. Here, we report a previously unrecognized role for the lipid fli...

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Detalles Bibliográficos
Autores principales: Lin, Zhi, Liu, Jiao, Long, Fei, Kang, Rui, Kroemer, Guido, Tang, Daolin, Yang, Minghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794750/
https://www.ncbi.nlm.nih.gov/pubmed/36575162
http://dx.doi.org/10.1038/s41467-022-35707-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794750/
https://www.ncbi.nlm.nih.gov/pubmed/36575162
http://dx.doi.org/10.1038/s41467-022-35707-2

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