SCON—a Short Conditional intrON for conditional knockout with one-step zygote injection

The generation of conditional alleles using CRISPR technology is still challenging. Here, we introduce a Short Conditional intrON (SCON, 189 bp) that enables the rapid generation of conditional alleles via one-step zygote injection. In this study, a total of 13 SCON mouse lines were successfully gen...

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Detalles Bibliográficos
Autores principales: Wu, Szu-Hsien Sam, Lee, Heetak, Szép-Bakonyi, Réka, Colozza, Gabriele, Boese, Ayse, Gert, Krista R., Hallay, Natalia, Lee, Ji-Hyun, Kim, Jihoon, Zhu, Yi, Linssen, Margot M., Pilat-Carotta, Sandra, Hohenstein, Peter, Theussl, Hans-Christian, Pauli, Andrea, Koo, Bon-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794761/
https://www.ncbi.nlm.nih.gov/pubmed/36494589
http://dx.doi.org/10.1038/s12276-022-00891-0

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