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ARHGAP17 regulates the spatiotemporal activity of Cdc42 at invadopodia

Invadopodia formation is regulated by Rho GTPases. However, the molecular mechanisms that control Rho GTPase signaling at invadopodia remain poorly understood. Here, we have identified ARHGAP17, a Cdc42-specific RhoGAP, as a key regulator of invadopodia in breast cancer cells and characterized a nov...

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Detalles Bibliográficos
Autores principales:	Kreider-Letterman, Gabriel, Castillo, Abel, Mahlandt, Eike K., Goedhart, Joachim, Rabino, Agustin, Goicoechea, Silvia, Garcia-Mata, Rafael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794838/ https://www.ncbi.nlm.nih.gov/pubmed/36571786 http://dx.doi.org/10.1083/jcb.202207020

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