Danger signals released during cold ischemia storage activate NLRP3 inflammasome in myeloid cells and influence early allograft function in liver transplantation

BACKGROUND: Innate immunity plays a fundamental role in solid organ transplantation. Myeloid cells can sense danger signals or DAMPs released after tissue or cell damage, such as during ischemia processes. This study aimed to identify DAMPs released during cold ischemia storage of human liver and an...

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Detalles Bibliográficos
Autores principales: Lucas-Ruiz, Fernando, Mateo, Sandra V., Jover-Aguilar, Marta, Alconchel, Felipe, Martínez-Alarcón, Laura, de Torre-Minguela, Carlos, Vidal-Correoso, Daniel, Villalba-López, Francisco, López-López, Víctor, Ríos-Zambudio, Antonio, Pons, José A., Ramírez, Pablo, Pelegrín, Pablo, Baroja-Mazo, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794897/
https://www.ncbi.nlm.nih.gov/pubmed/36543018
http://dx.doi.org/10.1016/j.ebiom.2022.104419

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