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Organophosphorus Poisoning among Patients Admitted to the Intensive Care Unit of Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study
INTRODUCTION: Organophosphates are potent cholinesterase inhibitors that when ingested in excessive amounts can be fatal. Organophosphorus poisoning has become an important clinical problem with increased mortality in the country from accidental or intentional ingestion of, or exposure to the pestic...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Journal of the Nepal Medical Association
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794948/ https://www.ncbi.nlm.nih.gov/pubmed/36705124 http://dx.doi.org/10.31729/jnma.7823 |
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author | Bhusal, Suzit Bhandari, Rupa Dahal, Sujata Niroula, Aliska Basnet, Krity Chaudhary, Ashlesha Pant, Subash |
author_facet | Bhusal, Suzit Bhandari, Rupa Dahal, Sujata Niroula, Aliska Basnet, Krity Chaudhary, Ashlesha Pant, Subash |
author_sort | Bhusal, Suzit |
collection | PubMed |
description | INTRODUCTION: Organophosphates are potent cholinesterase inhibitors that when ingested in excessive amounts can be fatal. Organophosphorus poisoning has become an important clinical problem with increased mortality in the country from accidental or intentional ingestion of, or exposure to the pesticide. This study aimed to find out the prevalence of organophosphorus poisoning among patients admitted to the Intensive Care Unit of Department of Internal Medicine in a tertiary care centre. METHODS: A descriptive cross-sectional study was conducted among patients admitted to the Intensive Care Unit of the Department of Internal Medicine in a tertiary care centre after receiving ethical approval from the Institutional Review Committee (Reference number: 2003202205). The study was conducted between 1 February 2021 and 1 February 2022 using hospital records. Convenience sampling was done among the patients who met the eligibility criteria. The diagnosis of organophosphorus poisoning was made based on the patient's history, clinical examination and the measurement of serum acetylcholinesterase levels. Point estimate and 95% Confidence Interval were calculated. RESULTS: Among 1108 patients admitted, organophosphorus poisoning was seen in 50 (4.51%) (3.295.73, 95% Confidence Interval). CONCLUSIONS: Our study found that the prevalence of organophosphorus poisoning was lower when compared to similar studies done in similar settings. |
format | Online Article Text |
id | pubmed-9794948 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Journal of the Nepal Medical Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-97949482022-12-30 Organophosphorus Poisoning among Patients Admitted to the Intensive Care Unit of Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study Bhusal, Suzit Bhandari, Rupa Dahal, Sujata Niroula, Aliska Basnet, Krity Chaudhary, Ashlesha Pant, Subash JNMA J Nepal Med Assoc Original Article INTRODUCTION: Organophosphates are potent cholinesterase inhibitors that when ingested in excessive amounts can be fatal. Organophosphorus poisoning has become an important clinical problem with increased mortality in the country from accidental or intentional ingestion of, or exposure to the pesticide. This study aimed to find out the prevalence of organophosphorus poisoning among patients admitted to the Intensive Care Unit of Department of Internal Medicine in a tertiary care centre. METHODS: A descriptive cross-sectional study was conducted among patients admitted to the Intensive Care Unit of the Department of Internal Medicine in a tertiary care centre after receiving ethical approval from the Institutional Review Committee (Reference number: 2003202205). The study was conducted between 1 February 2021 and 1 February 2022 using hospital records. Convenience sampling was done among the patients who met the eligibility criteria. The diagnosis of organophosphorus poisoning was made based on the patient's history, clinical examination and the measurement of serum acetylcholinesterase levels. Point estimate and 95% Confidence Interval were calculated. RESULTS: Among 1108 patients admitted, organophosphorus poisoning was seen in 50 (4.51%) (3.295.73, 95% Confidence Interval). CONCLUSIONS: Our study found that the prevalence of organophosphorus poisoning was lower when compared to similar studies done in similar settings. Journal of the Nepal Medical Association 2022-09 2022-09-30 /pmc/articles/PMC9794948/ /pubmed/36705124 http://dx.doi.org/10.31729/jnma.7823 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Bhusal, Suzit Bhandari, Rupa Dahal, Sujata Niroula, Aliska Basnet, Krity Chaudhary, Ashlesha Pant, Subash Organophosphorus Poisoning among Patients Admitted to the Intensive Care Unit of Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study |
title | Organophosphorus Poisoning among Patients Admitted to the Intensive Care Unit of Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study |
title_full | Organophosphorus Poisoning among Patients Admitted to the Intensive Care Unit of Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study |
title_fullStr | Organophosphorus Poisoning among Patients Admitted to the Intensive Care Unit of Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study |
title_full_unstemmed | Organophosphorus Poisoning among Patients Admitted to the Intensive Care Unit of Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study |
title_short | Organophosphorus Poisoning among Patients Admitted to the Intensive Care Unit of Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study |
title_sort | organophosphorus poisoning among patients admitted to the intensive care unit of department of internal medicine in a tertiary care centre: a descriptive cross-sectional study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794948/ https://www.ncbi.nlm.nih.gov/pubmed/36705124 http://dx.doi.org/10.31729/jnma.7823 |
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